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Int J Hyperthermia. 2017 Jun;33(4):428-434. doi: 10.1080/02656736.2017.1283064. Epub 2017 Feb 06.

Cardiac and respiratory effects of deep regional hyperthermia using an 8 MHz radiofrequency-capacitive device on patients with cancer.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

Rieko Izukura, Hajime Imada, Nobuko Hashiguchi, Hiroyuki Sawatari, Takayuki Ohguri, Mami Miyazono, Shin Ohta, Chiduko Takakura, Keiko Yamasaki, Chie Magota, Kanae Fujita, Hiromi Kuroda, Hideki Hirata, Tomoko Ohkusa, Akiko Chishaki

Affiliations

  1. a Department of Health Sciences , Kyushu University Graduate School of Medical Sciences , Fukuoka , Japan.
  2. b Cancer Treatment Center , Tobata Kyoritsu Hospital , Kitakyushu , Japan.
  3. c Department of Radiology , University of Occupational and Environmental Health , Kitakyushu , Japan.
  4. d School of Nursing , Fukuoka Prefectural University , Fukuoka , Japan.
  5. e Department of radiotherapy , St. Mary's Hospital , Kurume , Japan.
  6. f Sleep Apnea Center, Kyushu University Hospital , Fukuoka , Japan.
  7. g Faculty of Health Sciences , Ube Frontier University , Yamaguchi , Japan.

PMID: 28093005 DOI: 10.1080/02656736.2017.1283064

Abstract

PURPOSE: Hyperthermia (HT), an adjuvant therapy for variable cancers, may cause physiological changes in the patients, which may lead to cardiovascular problems. Among various HT treatments, the physiological effects of deep regional HT are still unclear. We examined the physiological alterations throughout deep regional HT to improve the HT safety.

MATERIALS AND METHODS: Thirty-one patients (age: 61 ± 12 years) with cancer received HT in the thoracic or upper abdominal regions using an 8-MHz radiofrequency-capacitive-device for 50 min. Rectal temperature (T

RESULTS: At 50 min after starting HT, T

CONCLUSIONS: Deep regional HT increased the deep body temperature and resulted in an increase of sweating with peripheral vasodilatation. Consequently, a significant reduction in BP would be induced on standing after HT. Careful attention is needed for patients receiving HT, especially when standing after HT.

Keywords: BP decrease on standing; Cancer therapy; adjuvant therapy; deep regional hyperthermia; radiofrequency capacitive device

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