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Oncol Lett. 2017 Jan;13(1):215-221. doi: 10.3892/ol.2016.5386. Epub 2016 Nov 15.

Molecular heterogeneity in the novel fusion gene .

Oncology letters

Takashi Okuda, Tomohiko Taki, Kazuhiro Nishida, Yoshiaki Chinen, Hisao Nagoshi, Chouhei Sakakura, Masafumi Taniwaki

Affiliations

  1. Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto 602-8566, Japan; Department of Hematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto 602-8566, Japan.
  2. Department of Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto 602-8566, Japan.
  3. Department of Hematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto 602-8566, Japan.
  4. Department of Digestive Surgery, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto 602-8566, Japan.

PMID: 28123544 PMCID: PMC5244987 DOI: 10.3892/ol.2016.5386

Abstract

Several novel fusion transcripts were identified by next-generation sequencing in gastric cancer; however, the breakpoint junctions have yet to be characterized. The present study characterized a plethora of

Keywords: APIP; FGFR2; gastric cancer; genomic amplification; homogenously staining region

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