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Aorta (Stamford). 2016 Aug 01;4(4):115-123. doi: 10.12945/j.aorta.2016.16.007. eCollection 2016 Aug.

Axillary Versus Femoral Arterial Cannulation During Repair of Type A Aortic Dissection?: An Old Problem Seeking New Solutions.

Aorta (Stamford, Conn.)

Sotiris C Stamou, Derek Gartner, Nicholas T Kouchoukos, Kevin W Lobdell, Kamal Khabbaz, Edward Murphy, Robert C Hagberg

Affiliations

  1. Department of Cardiovascular Surgery, Baystate Medical Center, Springfield, Massachusetts, USA.
  2. Division of Cardiothoracic Surgery, Missouri Baptist Medical Center, Saint Louis, Missouri, USA.
  3. Department of Thoracic and Cardiovascular Surgery, Sanger Heart and Vascular Institute, Carolinas Medical Center, Charlotte, North Carolina, USA.
  4. Division of Cardiac Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
  5. Thoracic and Cardiovascular Surgery, Spectrum Health, Fred and Lena Meijer Heart and Vascular Institute, Grand Rapids, Michigan, USA.
  6. Department of Cardiac Surgery, Hartford Hospital, Hartford, Connecticut, USA.

PMID: 28097193 PMCID: PMC5217728 DOI: 10.12945/j.aorta.2016.16.007

Abstract

BACKGROUND: The goal of this study was to compare early postoperative outcomes and actuarial-free survival between patients who underwent repair of acute Type A aortic dissection with axillary or femoral artery cannulation.

METHODS: A total of 305 patients from five academic medical centers underwent acute Type A aortic dissection repair via axillary (

RESULTS: Operative mortality was not influenced by cannulation site (16% for axillary cannulation vs. 19% for femoral cannulation, p = 0.64). In multivariate logistic regression analysis, hemodynamic instability (p < 0.001) and prolonged cardiopulmonary bypass time (>200 min; p = 0.05) emerged as independent predictors of operative mortality. Stroke rates were comparable between the two techniques (14% for axillary and 17% for femoral cannulation, p = 0.52). Five-year actuarial survival was comparable between the groups (55.1% for axillary and 65.7% for femoral cannulation, p = 0.36). In Cox regression analysis, predictors of long-term mortality were: age (p < 0.001), stroke (p < 0.001), prolonged cardiopulmonary bypass time (p = 0.001), hemodynamic instability (p = 0.002), and renal failure (p = 0.001).

CONCLUSIONS: The outcomes of femoral versus axillary arterial cannulation in patients with acute Type A aortic dissection are comparable. The choice of arterial cannulation site should be individualized based on different patient risk profiles.

Keywords: Aorta; Aortic dissection; Axillary cannulation; Dissection; Femoral cammulation; Outcomes

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