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Case Rep Gastroenterol. 2017 Jan 06;10(3):814-818. doi: 10.1159/000454674. eCollection 2016.

Plasmapheresis for Refractory Pruritus due to Drug-Induced Cholestasis.

Case reports in gastroenterology

Hasan Al-Azzawi, Ruchi Patel, Gagan Sood, Sumit Kapoor

Affiliations

  1. Department of Pulmonary, Critical Care and Sleep, Baylor College of Medicine, Houston, TX, USA.
  2. Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, USA.

PMID: 28203129 PMCID: PMC5260533 DOI: 10.1159/000454674

Abstract

Pruritus can be a distressing symptom seen in various cholestatic disorders. It is treated with medications like bile acid sequestrants. Drug-induced cholestasis usually resolves with withdrawal of the causative medication. We describe a case of refractory pruritus due to drug-induced cholestasis, not improved with withdrawal of the drug, managed effectively with multiple sessions of plasmapheresis.

Keywords: Cholestasis; Drug-induced cholestasis; Plasmapheresis; Pruritus; Refractory

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