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Evans DL, Leserman J, Pedersen CA, et al. Immune correlates of stress and depression. Psychopharmacol Bull. 1989;25(3):319-24
Evans, D. L., Leserman, J., Pedersen, C. A., Golden, R. N., Lewis, M. H., Folds, J. A., & Ozer, H. (1989). Immune correlates of stress and depression. Psychopharmacology bulletin, 25(3), 319-24.
Evans, D L, et al. "Immune correlates of stress and depression." Psychopharmacology bulletin vol. 25,3 (1989): 319-24.
Evans DL, Leserman J, Pedersen CA, Golden RN, Lewis MH, Folds JA, Ozer H. Immune correlates of stress and depression. Psychopharmacol Bull. 1989;25(3):319-24. PMID: 2697005.
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Psychopharmacol Bull. 1989;25(3):319-24.

Immune correlates of stress and depression.

Psychopharmacology bulletin

D L Evans, J Leserman, C A Pedersen, R N Golden, M H Lewis, J A Folds, H Ozer

PMID: 2697005

Abstract

This paper reviews the evidence for alterations in immunity associated with depression and stressful events. The reviewed studies examine a variety of immune parameters (e.g., mitogen response, natural killer cell activity and number, T-cell, and T-cell subpopulations) in relation to depression and in relation to a number of stressful events (e.g., death of spouse, examinations). There is considerable variability in the findings of the available studies. However, the review finds considerable evidence for an association between a variety of stressful events and lowered immunity and between severe depression and lowered immunity. The clinical relevance of these psychoimmune relationships remains in question.

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