Display options
Cite
Fasanya AA, Loncharich MF, Gandhi V, et al. Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance. Cureus. 2016;8(11):e899doi: 10.7759/cureus.899.
Fasanya, A. A., Loncharich, M. F., Gandhi, V., Rana, S., & Balaan, M. (2016). Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance. Cureus, 8(11), e899. https://doi.org/10.7759/cureus.899
Fasanya, Adebayo A, et al. "Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance." Cureus vol. 8,11 (2016): e899. doi: https://doi.org/10.7759/cureus.899
Fasanya AA, Loncharich MF, Gandhi V, Rana S, Balaan M. Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance. Cureus. 2016 Nov 28;8(11):e899. doi: 10.7759/cureus.899. PMID: 28070468; PMCID: PMC5208555.
Copy Download .nbib Format: NLM
Share it on

Cureus. 2016 Nov 28;8(11):e899. doi: 10.7759/cureus.899.

Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance.

Cureus

Adebayo A Fasanya, Michael F Loncharich, Viral Gandhi, Sandeep Rana, Marvin Balaan

Affiliations

  1. Pulmonary and Critical Care Medicine, Allegheny General Hospital.
  2. Medicine, Temple University School of Medicine.
  3. Neurology, Allegheny General Hospital.

PMID: 28070468 PMCID: PMC5208555 DOI: 10.7759/cureus.899

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease presenting with weakness and numbness in a remitting or chronic progressive course. It is known to have several clinical presentations and several associated diseases. CIDP has been associated with multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), and other paraproteinemias. We present a case of refractory CIDP in which the initial workup for multiple myeloma was negative, and multiple myeloma was then diagnosed two and half years later. Treatment of the multiple myeloma led to clinical improvement. This case is instructive in that perhaps more frequent surveillance for paraproteinemia in patients with CIPD, even after a negative initial workup, could lead to a better clinical outcome.

Keywords: cidp; neuropathy; paraproteinemia; weakness

Conflict of interest statement

The authors have declared that no competing interests exist.

References

  1. Curr Opin Neurol. 2009 Oct;22(5):480-5 - PubMed
  2. Micron. 2008;39(2):61-70 - PubMed
  3. Eur J Neurol. 2011 Nov;18(11):1291-8 - PubMed
  4. Neurology. 1981 Nov;31(11):1480-3 - PubMed
  5. J Neurol Sci. 2016 Mar 15;362:188-95 - PubMed
  6. Hematol Oncol. 2008 Jun;26(2):55-65 - PubMed
  7. BMC Neurol. 2016 Jan 28;16:13 - PubMed
  8. Presse Med. 2013 Jun;42(6 Pt 2):e203-15 - PubMed
  9. Brain. 1995 Apr;118 ( Pt 2):359-68 - PubMed
  10. J Neurol Sci. 1999 Mar 15;164(1):64-71 - PubMed

Publication Types