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Bukovsky A. Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment. World J Stem Cells. 2016;8(12):399-427doi: 10.4252/wjsc.v8.i12.399.
Bukovsky, A. (2016). Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment. World journal of stem cells, 8(12), 399-427. https://doi.org/10.4252/wjsc.v8.i12.399
Bukovsky, Antonin. "Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment." World journal of stem cells vol. 8,12 (2016): 399-427. doi: https://doi.org/10.4252/wjsc.v8.i12.399
Bukovsky A. Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment. World J Stem Cells. 2016 Dec 26;8(12):399-427. doi: 10.4252/wjsc.v8.i12.399. PMID: 28074124; PMCID: PMC5183987.
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World J Stem Cells. 2016 Dec 26;8(12):399-427. doi: 10.4252/wjsc.v8.i12.399.

Involvement of blood mononuclear cells in the infertility, age-associated diseases and cancer treatment.

World journal of stem cells

Antonin Bukovsky

Affiliations

  1. Antonin Bukovsky, Laboratory of Reproductive Biology BIOCEV, Institute of Biotechnology Czech Academy of Sciences, 25250 Vestec, Czech Republic.

PMID: 28074124 PMCID: PMC5183987 DOI: 10.4252/wjsc.v8.i12.399

Abstract

Blood mononuclear cells consist of T cells and monocyte derived cells. Beside immunity, the blood mononuclear cells belong to the complex tissue control system (TCS), where they exhibit morphostatic function by stimulating proliferation of tissue stem cells followed by cellular differentiation, that is stopped after attaining the proper functional stage, which differs among various tissue types. Therefore, the term immune and morphostatic system (IMS) should be implied. The TCS-mediated morphostasis also consists of vascular pericytes controlled by autonomic innervation, which is regulating the quantity of distinct tissues

Keywords: Age-associated diseases; Blood mononuclear cells; Cancer immunotherapy; Immune system; Infertility treatment; Regenerative medicine; Stem cells; Tissue control system; Tissue morphostasis; Transfusion morphostatic treatment

Conflict of interest statement

Conflict-of-interest statement: The author declares no conflict of interest for this article.

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