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Data Brief. 2017 Feb 22;11:413-427. doi: 10.1016/j.dib.2017.02.044. eCollection 2017 Apr.

TH1 and TH2 cytokine data in insulin secretagogues users newly diagnosed with breast cancer.

Data in brief

Zachary A P Wintrob, Jeffrey P Hammel, George K Nimako, Dan P Gaile, Alan Forrest, Alice C Ceacareanu

Affiliations

  1. State University of New York at Buffalo, Dept. of Pharmacy Practice, NYS Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, NY 14203, United States.
  2. Cleveland Clinic, Dept. of Biostatistics and Epidemiology, 9500 Euclid Ave., Cleveland, OH 44195, United States.
  3. State University of New York at Buffalo, Dept. of Biostatistics, 718 Kimball Tower, Buffalo, NY 14214, United States.
  4. The UNC Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, Campus Box 7569, Chapel Hill, NC 27599, United States.
  5. State University of New York at Buffalo, Dept. of Pharmacy Practice, NYS Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, NY 14203, United States; Roswell Park Cancer Institute, Dept. of Pharmacy Services, Elm & Carlton Streets, Buffalo, NY 14263, United States.

PMID: 28280762 PMCID: PMC5333503 DOI: 10.1016/j.dib.2017.02.044

Abstract

Stimulation of insulin production by insulin secretagogue use may impact T helper cells' cytokine production. This dataset presents the relationship between baseline insulin secretagogues use in women diagnosed with breast cancer and type 2 diabetes mellitus, the T-helper 1 and 2 produced cytokine profiles at the time of breast cancer diagnosis, and subsequent cancer outcomes. A Pearson correlation analysis evaluating the relationship between T-helper cytokines stratified by of insulin secretagogues use and controls is also provided.

Keywords: Breast cancer; Cancer outcomes; Cancer prognosis; Cytokine; Diabetes; Secretagogue; TH1 cytokine; TH2 cytokine; Type 1T helper cytokine; Type 2T helper cytokine

References

  1. Cytokine. 2017 Jan;89:45-61 - PubMed

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