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Sci Rep. 2017 Mar 03;7:43668. doi: 10.1038/srep43668.

A Peptide Amphiphile Organogelator of Polar Organic Solvents.

Scientific reports

Charlotte K Rouse, Adam D Martin, Christopher J Easton, Pall Thordarson

Affiliations

  1. Research School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia.
  2. School of Chemistry, The Australian Centre for Nanomedicine and the ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of New South Wales, Sydney, NSW 2052, Australia.

PMID: 28255169 PMCID: PMC5334642 DOI: 10.1038/srep43668

Abstract

A peptide amphiphile is reported, that gelates a range of polar organic solvents including acetonitrile/water, N,N-dimethylformamide and acetone, in a process dictated by β-sheet interactions and facilitated by the presence of an alkyl chain. Similarities with previously reported peptide amphiphile hydrogelators indicate analogous underlying mechanisms of gelation and structure-property relationships, suggesting that peptide amphiphile organogel design may be predictably based on hydrogel precedents.

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