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Sinacki M, Serkies K, Dziadziuszko R, et al. Radiation dose to the left anterior descending coronary artery during interstitial pulsed-dose-rate brachytherapy used as a boost in breast cancer patients undergoing organ-sparing treatment. J Contemp Brachytherapy. 2017;9(1):7-13doi: 10.5114/jcb.2017.66043.
Sinacki, M., Serkies, K., Dziadziuszko, R., Narkowicz, M., Kamińska, J., & Lipniewicz, J. (2017). Radiation dose to the left anterior descending coronary artery during interstitial pulsed-dose-rate brachytherapy used as a boost in breast cancer patients undergoing organ-sparing treatment. Journal of contemporary brachytherapy, 9(1), 7-13. https://doi.org/10.5114/jcb.2017.66043
Sinacki, Marcin, et al. "Radiation dose to the left anterior descending coronary artery during interstitial pulsed-dose-rate brachytherapy used as a boost in breast cancer patients undergoing organ-sparing treatment." Journal of contemporary brachytherapy vol. 9,1 (2017): 7-13. doi: https://doi.org/10.5114/jcb.2017.66043
Sinacki M, Serkies K, Dziadziuszko R, Narkowicz M, Kamińska J, Lipniewicz J. Radiation dose to the left anterior descending coronary artery during interstitial pulsed-dose-rate brachytherapy used as a boost in breast cancer patients undergoing organ-sparing treatment. J Contemp Brachytherapy. 2017 Feb;9(1):7-13. doi: 10.5114/jcb.2017.66043. Epub 2017 Feb 15. PMID: 28344598; PMCID: PMC5346609.
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J Contemp Brachytherapy. 2017 Feb;9(1):7-13. doi: 10.5114/jcb.2017.66043. Epub 2017 Feb 15.

Radiation dose to the left anterior descending coronary artery during interstitial pulsed-dose-rate brachytherapy used as a boost in breast cancer patients undergoing organ-sparing treatment.

Journal of contemporary brachytherapy

Marcin Sinacki, Krystyna Serkies, Rafał Dziadziuszko, Magdalena Narkowicz, Joanna Kamińska, Joanna Lipniewicz

Affiliations

  1. Department of Oncology and Radiotherapy, Medical University of Gdansk.
  2. Department of Oncology and Radiotherapy, Medical University of Gdansk; Institute of Experimental Physics, Faculty of Mathematics, Physics and Informatics, University of Gdansk, Poland.

PMID: 28344598 PMCID: PMC5346609 DOI: 10.5114/jcb.2017.66043

Abstract

PURPOSE: To assess dose received by the left anterior descending (LAD) coronary artery during interstitial pulsed-dose-rate brachytherapy (PDR-BT) boost for left-sided breast cancer patients undergoing organ-sparing treatment.

MATERIAL AND METHODS: Thirty consecutive pT1-3N0-1M0 breast cancer patients boosted between 2014 and 2015 with 10 Gy/10 pulses/hour PDR-BT following a computed tomography (CT) simulation with the multi-catheter implant were included. The most common localization of primary tumor were upper quadrants. Patients were implanted with rigid tubes following breast conserving surgery and whole breast external beam irradiation (40 Gy/15 or 50 Gy/25 fractions). Computed tomography scans were retrospectively reviewed and LADs were contoured without and with margin of 5 mm (LAD

RESULTS: The mean D

CONCLUSIONS: Interstitial multi-catheter PDR-BT used as a boost for left-sided breast cancer is generally associated with low dose to the LAD. However, higher dose in individual cases may require alternative approaches.

Keywords: LAD; breast carcinoma; pulsed-dose-rate brachytherapy

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