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Mazurkiewicz Ł, Rużyłło W, Chmielak Z, et al. ANP and BNP plasma levels in patients with rheumatic mitral stenosis after percutaneous balloon mitral valvuloplasty. Postepy Kardiol Interwencyjnej. 2017;13(1):18-25doi: 10.5114/aic.2017.66182.
Mazurkiewicz, �. �., Rużyłło, W., Chmielak, Z., Opalińska-Ciszek, E., Janas, J., Hoffman, P., Hryniewiecki, T., & Grzybowski, J. (2017). ANP and BNP plasma levels in patients with rheumatic mitral stenosis after percutaneous balloon mitral valvuloplasty. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 13(1), 18-25. https://doi.org/10.5114/aic.2017.66182
Mazurkiewicz, Łukasz, et al. "ANP and BNP plasma levels in patients with rheumatic mitral stenosis after percutaneous balloon mitral valvuloplasty." Postepy w kardiologii interwencyjnej = Advances in interventional cardiology vol. 13,1 (2017): 18-25. doi: https://doi.org/10.5114/aic.2017.66182
Mazurkiewicz Ł, Rużyłło W, Chmielak Z, Opalińska-Ciszek E, Janas J, Hoffman P, Hryniewiecki T, Grzybowski J. ANP and BNP plasma levels in patients with rheumatic mitral stenosis after percutaneous balloon mitral valvuloplasty. Postepy Kardiol Interwencyjnej. 2017;13(1):18-25. doi: 10.5114/aic.2017.66182. Epub 2017 Mar 10. PMID: 28344613; PMCID: PMC5364278.
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Postepy Kardiol Interwencyjnej. 2017;13(1):18-25. doi: 10.5114/aic.2017.66182. Epub 2017 Mar 10.

ANP and BNP plasma levels in patients with rheumatic mitral stenosis after percutaneous balloon mitral valvuloplasty.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Łukasz Mazurkiewicz, Witold Rużyłło, Zbigniew Chmielak, Ewa Opalińska-Ciszek, Jadwiga Janas, Piotr Hoffman, Tomasz Hryniewiecki, Jacek Grzybowski

Affiliations

  1. Department of Cardiomyopathies, CMR Unit, Institute of Cardiology, Warsaw, Poland.
  2. Institute of Cardiology, Warsaw, Poland.
  3. Department of Cardiology and Interventional Angiology, Institute of Cardiology, Warsaw, Poland.
  4. Department of Congenital Cardiac Defects, Institute of Cardiology, Warsaw, Poland.
  5. Department of Acquired Cardiac Defects, Institute of Cardiology, Warsaw, Poland.
  6. Department of Cardiomyopathies, Institute of Cardiology, Warsaw, Poland.

PMID: 28344613 PMCID: PMC5364278 DOI: 10.5114/aic.2017.66182

Abstract

INTRODUCTION: Atrial (ANP) and B-type (BNP) natriuretic peptides are hormones secreted by the heart as a response to volume expansion and pressure overload.

AIM: To assess the changes of ANP and BNP after percutaneous balloon mitral valvuloplasty (PBMV) and to investigate factors associated with endpoints.

MATERIAL AND METHODS: The study included 96 patients (90.7% females, age 51.6 ±12.2 years) with rheumatic mitral valve stenosis (mitral valve area (MVA) 1.18 (1.01-1.33) cm

RESULTS: The PBMV was successful in all cases. After the procedure MVA increased (1.18-1.78 cm

CONCLUSIONS: Patients with MS had increased levels of both BNP and ANP. Baseline NYHA class was found to be associated with outcomes after the procedure.

Keywords: mitral stenosis; neurohormones; percutaneous mitral valvuloplasty

Conflict of interest statement

The authors declare no conflict of interest.

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