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Oncoimmunology. 2016 Sep 27;6(2):e1216291. doi: 10.1080/2162402X.2016.1216291. eCollection 2017.

Zoledronic acid boosts γδ T-cell activity in children receiving αβ.

Oncoimmunology

A Bertaina, A Zorzoli, A Petretto, G Barbarito, E Inglese, P Merli, C Lavarello, L P Brescia, B De Angelis, G Tripodi, L Moretta, F Locatelli, I Airoldi

Affiliations

  1. Department of Pediatric Hematology and Oncology, IRCCS Ospedale Bambino Gesù , Rome, Italy.
  2. Laboratorio di Oncologia, Istituto Giannina Gaslini , Genova, Italy.
  3. Core Facilities, Istituto Giannina Gaslini , Genova, Italy.
  4. Dipartimento Ricerca Traslazionale, Medicina di Laboratorio, Diagnostica e Servizi, Istituto Giannina Gaslini , Genova, Italy.
  5. Area di Ricerca Immunologica, IRCCS Ospedale Bambino Gesù , Rome, Italy.
  6. Department of Pediatric Hematology and Oncology, IRCCS Ospedale Bambino Gesù, Rome, Italy; Department of Pediatric Science, Università di Pavia, Pavia, Italy.

PMID: 28344861 PMCID: PMC5353934 DOI: 10.1080/2162402X.2016.1216291

Abstract

We demonstrated that γδ T cells of patients given HLA-haploidentical HSCT after removal of αβ

Keywords: haematopoietic stem cell transplantation; leukemic patients; proteomic; zoledronic acid; γδ T cells

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