Display options
Cite
Al-Turki DA, Al-Omar MA, Abou-Zeid LA, et al. Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors. Saudi Pharm J. 2015;25(1):59-69doi: 10.1016/j.jsps.2015.07.001.
Al-Turki, D. A., Al-Omar, M. A., Abou-Zeid, L. A., Shehata, I. A., & Al-Awady, M. S. (2017). Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 25(1), 59-69. https://doi.org/10.1016/j.jsps.2015.07.001
Al-Turki, Deema A, et al. "Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors." Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society vol. 25,1 (2017): 59-69. doi: https://doi.org/10.1016/j.jsps.2015.07.001
Al-Turki DA, Al-Omar MA, Abou-Zeid LA, Shehata IA, Al-Awady MS. Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors. Saudi Pharm J. 2017 Jan;25(1):59-69. doi: 10.1016/j.jsps.2015.07.001. Epub 2015 Jul 26. PMID: 28223863; PMCID: PMC5310148.
Copy Download .nbib Format: NLM
Share it on

Saudi Pharm J. 2017 Jan;25(1):59-69. doi: 10.1016/j.jsps.2015.07.001. Epub 2015 Jul 26.

Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Deema A Al-Turki, Mohamed A Al-Omar, Laila A Abou-Zeid, Ihsan A Shehata, Mohammed S Al-Awady

Affiliations

  1. Department of Pharmaceutical Chemistry, College of Pharmacy, P.O. Box 2457, King Saud University, Riyadh 11451, Saudi Arabia.
  2. Department of Organic Pharmaceutical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
  3. Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
  4. Department of Pharmacology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

PMID: 28223863 PMCID: PMC5310148 DOI: 10.1016/j.jsps.2015.07.001

Abstract

New series of 3,4-diaryl-2-thioxoimidazolidin-4-ones and 3-alkylthio-4,5-diaryl-4

Keywords: Anti-inflammatory; Docking; Selective COX-2 inhibitors; Synthesis

References

  1. Bioorg Med Chem. 2006 Feb 15;14(4):918-27 - PubMed
  2. Arzneimittelforschung. 1991 Dec;41(12):1260-4 - PubMed
  3. Am J Med. 1994 Mar;96(3):274-81 - PubMed
  4. Nature. 1996 Dec 19-26;384(6610):644-8 - PubMed
  5. Ann Intern Med. 1991 Feb 15;114(4):257-63 - PubMed
  6. J Med Chem. 2000 May 4;43(9):1661-3 - PubMed
  7. Gastrointest Endosc Clin N Am. 1996 Jul;6(3):489-504 - PubMed
  8. FASEB J. 1998 Sep;12(12):1063-73 - PubMed
  9. J Med Chem. 1997 Apr 25;40(9):1347-65 - PubMed
  10. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3181-6 - PubMed
  11. Am J Med. 1998 Jul 27;105(1B):31S-38S - PubMed
  12. Proc Soc Exp Biol Med. 1962 Dec;111:544-7 - PubMed
  13. J Pharm Pharmacol. 1968 Jul;20(7):567-9 - PubMed
  14. Gastroenterol Clin North Am. 1996 Jun;25(2):279-98 - PubMed
  15. Postgrad Med. 2001 May;109(5):117-20, 123-8 - PubMed
  16. J Med Chem. 2000 Mar 9;43(5):775-7 - PubMed
  17. Bioorg Med Chem Lett. 2003 Feb 24;13(4):597-600 - PubMed
  18. Biochemistry. 1996 Jun 11;35(23):7330-40 - PubMed
  19. Arthritis Rheum. 2000 Jan;43(1):4-13 - PubMed
  20. J Med Chem. 1984 Dec;27(12):1565-70 - PubMed
  21. Gastroenterol Clin North Am. 2001 Dec;30(4):1011-25, viii - PubMed
  22. Bioorg Med Chem. 2006 Apr 15;14(8):2507-17 - PubMed
  23. Eur J Med Chem. 2004 Jun;39(6):535-45 - PubMed
  24. Am Fam Physician. 2000 Jun 15;61(12):3669-76 - PubMed
  25. Rheum Dis Clin North Am. 1995 Aug;21(3):741-58 - PubMed
  26. Anal Chem. 1985 Jun;57(7):1170-3 - PubMed
  27. Arch Intern Med. 1998 Jan 12;158(1):33-9 - PubMed
  28. J Gerontol. 1993 May;48(3):M91-6 - PubMed

Publication Types