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Asian Pac J Cancer Prev. 2017 Feb 01;18(2):421-424. doi: 10.22034/APJCP.2017.18.2.421.

Epidemiological Characteristics of Retinoblastoma in Children Attending Almouassat University Hospital, Damascus, Syria, 2012-2016.

Asian Pacific journal of cancer prevention : APJCP

Ahmad Al Hasan, Rashad Murad, Khaldoun Zaid, Jourjous Al Daoud, Khaled Zaid

Affiliations

  1. Department of Ophthalmology, Damascus University, Al Mouassat University Hospital, Damascus, Syria. Email:ophth. [email protected]

PMID: 28345824 PMCID: PMC5454737 DOI: 10.22034/APJCP.2017.18.2.421

Abstract

Retinoblastoma (Rb) is a malignant tumor that originates from the developing retina. Diagnosis is based on clinical signs and symptoms and usually children under the age of five years are affected. Early diagnosis and treatment of Rb and non-ocular tumors can reduce morbidity and increase longevity. Treatment in the early stages may allow a good prognosis and salvage of visual function.The aim of this study is to present descriptive epidemiological aspects of retinoblastomas in children seen at Almouassat University Hospital (AUH) in Damascus, Syria from 1 January 2012 to 31 October 2016In this retrospective, observational hospital survey, medical records of 37 retinoblastoma cases were reviewed. The male/female (M/F) ratio was 1.6. The most frequent presenting sign was leukocoria (56.7%) and 81% of cases were diagnosed between the ages of 4 months and 3 years. More than 73% of cases were diagnosed early at stages I and II.

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Keywords: Retinoblastoma; epidemiology; children; Syria

References

  1. Jpn J Clin Oncol. 2011 Mar;41(3):373-9 - PubMed
  2. Br J Ophthalmol. 2009 Jan;93(1):33-7 - PubMed
  3. Br J Ophthalmol. 2009 Jan;93(1):38-9 - PubMed
  4. Expert Opin Drug Discov. 2013 Apr;8(4):383-94 - PubMed
  5. Br J Ophthalmol. 2009 Jan;93(1):21-3 - PubMed
  6. Klin Oczna. 1994 Jan;96(1):21-3 - PubMed
  7. Int J Ophthalmol. 2013 Aug 18;6(4):481-6 - PubMed
  8. Am J Ophthalmol. 2014 May;157(5):1109-15 - PubMed
  9. Pediatr Blood Cancer. 2009 Feb;52(2):215-7 - PubMed
  10. J Pediatr Ophthalmol Strabismus. 2013 Mar-Apr;50(2):106-12 - PubMed
  11. Drug Deliv. 2016 Sep;23 (7):2488-2496 - PubMed
  12. Clin Exp Ophthalmol. 2010 Aug;38(6):638-43 - PubMed
  13. West Afr J Med. 1993 Oct-Dec;12(4):223-7 - PubMed
  14. Ann Oncol. 2007 Oct;18(10):1722-33 - PubMed
  15. Acta Ophthalmol. 2016 Nov;94(7):e644-e651 - PubMed
  16. Eur J Cancer. 2006 Sep;42(13):2092-102 - PubMed
  17. Paediatr Perinat Epidemiol. 2002 Oct;16(4):370-4 - PubMed
  18. Asian Pac J Cancer Prev. 2014;15(18):7805-9 - PubMed
  19. Acta Ophthalmol. 2016 Mar;94(2):165-74 - PubMed
  20. Asian Pac J Cancer Prev. 2014;15(6):2847-50 - PubMed
  21. Pediatr Hematol Oncol. 1998 Nov-Dec;15(6):501-8 - PubMed
  22. Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):784-92 - PubMed
  23. J Fr Ophtalmol. 2015 Jun;38(6):550-8 - PubMed
  24. Nippon Ganka Gakkai Zasshi. 2007 Apr;111(4):350-1 - PubMed
  25. Br J Ophthalmol. 2009 Sep;93(9):1159-62 - PubMed
  26. Pediatrics. 2003 Dec;112(6 Pt 1):1248-55 - PubMed
  27. Asian Pac J Cancer Prev. 2014;15(18):7863-7 - PubMed
  28. Eye (Lond). 2013 Feb;27(2):128-36 - PubMed
  29. Asian Pac J Cancer Prev. 2015;16(16):6899-902 - PubMed

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