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Gevorgyan A, Bregni G, Galli G, et al. HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature. Breast Care (Basel). 2016;11(6):424-426doi: 10.1159/000453572.
Gevorgyan, A., Bregni, G., Galli, G., Zanardi, E., de Braud, F., & Di Cosimo, S. (2016). HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature. Breast care (Basel, Switzerland), 11(6), 424-426. https://doi.org/10.1159/000453572
Gevorgyan, Arpine, et al. "HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature." Breast care (Basel, Switzerland) vol. 11,6 (2016): 424-426. doi: https://doi.org/10.1159/000453572
Gevorgyan A, Bregni G, Galli G, Zanardi E, de Braud F, Di Cosimo S. HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature. Breast Care (Basel). 2016 Dec;11(6):424-426. doi: 10.1159/000453572. Epub 2016 Dec 09. PMID: 28228710; PMCID: PMC5290429.
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Breast Care (Basel). 2016 Dec;11(6):424-426. doi: 10.1159/000453572. Epub 2016 Dec 09.

HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature.

Breast care (Basel, Switzerland)

Arpine Gevorgyan, Giacomo Bregni, Giulia Galli, Elisa Zanardi, Filippo de Braud, Serena Di Cosimo

Affiliations

  1. Department of Medical Oncology, Fondazione IRCCS, Istituto Nazionale Tumori, Milan, Italy.
  2. Medical Oncology Unit 1, IRCCS AOU San Martino-IST, Genoa, Italy.

PMID: 28228710 PMCID: PMC5290429 DOI: 10.1159/000453572

Abstract

BACKGROUND: Neuroendocrine carcinoma is an uncommon histology for breast cancer.

CASE REPORT: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.

Keywords: Breast carcinoma; Neuroendocrine carcinoma; Trastuzumab

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