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Roatt BM, Aguiar-Soares RD, Reis LE, et al. A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden. Front Immunol. 2017;8:217doi: 10.3389/fimmu.2017.00217.
Roatt, B. M., Aguiar-Soares, R. D., Reis, L. E., Cardoso, J. M., Mathias, F. A., de Brito, R. C., da Silva, S. M., Gontijo, N. F., Ferreira, S. A., Valenzuela, J. G., Corrêa-Oliveira, R., Giunchetti, R. C., & Reis, A. B. (2017). A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden. Frontiers in immunology, 8217. https://doi.org/10.3389/fimmu.2017.00217
Roatt, Bruno Mendes, et al. "A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden." Frontiers in immunology vol. 8 (2017): 217. doi: https://doi.org/10.3389/fimmu.2017.00217
Roatt BM, Aguiar-Soares RD, Reis LE, Cardoso JM, Mathias FA, de Brito RC, da Silva SM, Gontijo NF, Ferreira SA, Valenzuela JG, Corrêa-Oliveira R, Giunchetti RC, Reis AB. A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden. Front Immunol. 2017 Mar 07;8:217. doi: 10.3389/fimmu.2017.00217. eCollection 2017. PMID: 28321217; PMCID: PMC5338076.
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Front Immunol. 2017 Mar 07;8:217. doi: 10.3389/fimmu.2017.00217. eCollection 2017.

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.

Frontiers in immunology

Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Fernando Augusto Siqueira Mathias, Rory Cristiane Fortes de Brito, Sydnei Magno da Silva, Nelder De Figueiredo Gontijo, Sidney de Almeida Ferreira, Jesus G Valenzuela, Rodrigo Corrêa-Oliveira, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis

Affiliations

  1. Laboratório de Imunopatologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Departamento de Patologia Clínica, COLTEC, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais (INCT-DT), Salvador, Brazil.
  2. Laboratório de Imunopatologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto , Ouro Preto, Minas Gerais , Brazil.
  3. Laboratório de Bioensaios em Leishmania, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia , Uberlândia, Minas Gerais , Brazil.
  4. Laboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia, Universidade Federal de Minas Gerais , Belo Horizonte, Minas Gerais , Brazil.
  5. Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Rockville, MD , USA.
  6. Laboratório de Imunopatologia, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais (INCT-DT), Salvador, Brazil.
  7. Laboratório de Biologia das Interações Celulares, Departamento de Morfologia, Universidade Federal de Minas Gerais , Belo Horizonte, Minas Gerais , Brazil.

PMID: 28321217 PMCID: PMC5338076 DOI: 10.3389/fimmu.2017.00217

Abstract

Herein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of

Keywords: L. infantum; canine visceral leishmaniasis; heterologous vaccine therapy; immune response; immunotherapy

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