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Keegan JD, Good B, de Waal T, et al. Genetic basis of benzimidazole resistance in . Ir Vet J. 2017;70:8doi: 10.1186/s13620-017-0087-8.
Keegan, J. D., Good, B., de Waal, T., Fanning, J., & Keane, O. M. (2017). Genetic basis of benzimidazole resistance in . Irish veterinary journal, 708. https://doi.org/10.1186/s13620-017-0087-8
Keegan, Jason D, et al. "Genetic basis of benzimidazole resistance in ." Irish veterinary journal vol. 70 (2017): 8. doi: https://doi.org/10.1186/s13620-017-0087-8
Keegan JD, Good B, de Waal T, Fanning J, Keane OM. Genetic basis of benzimidazole resistance in . Ir Vet J. 2017 Feb 13;70:8. doi: 10.1186/s13620-017-0087-8. eCollection 2017. PMID: 28228936; PMCID: PMC5307811.
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Ir Vet J. 2017 Feb 13;70:8. doi: 10.1186/s13620-017-0087-8. eCollection 2017.

Genetic basis of benzimidazole resistance in .

Irish veterinary journal

Jason D Keegan, Barbara Good, Theo de Waal, June Fanning, Orla M Keane

Affiliations

  1. Animal and Bioscience Department, Teagasc, Grange, Dunsany, Co. Meath, Ireland.
  2. School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
  3. Animal & Bioscience Dept, Teagasc, Mellows Campus, Athenry, Co. Galway, Ireland.
  4. Department of Agriculture Food and the Marine, Central Veterinary Research Laboratory, Backweston, Co. Kildare, Ireland.

PMID: 28228936 PMCID: PMC5307811 DOI: 10.1186/s13620-017-0087-8

Abstract

Resistance to benzimidazole (BZ) anthelmintics is common in ovine nematodes of economic importance. Single nucleotide polymorphisms (SNP) at three positions in the isotype 1 β- tubulin gene have been associated with BZ resistance and molecular tests for the detection of BZ resistance have been developed. In order to determine if such tests are practicable in Ireland the polymorphisms associated with BZ resistance must be identified. To this end, BZ-resistant nematodes were recovered from four farms in Ireland. Resistant

Keywords: Anthelmintic; Benzimidazole; Resistance; Sheep; Teladorsagia; β-tubulin

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