Display options
Share it on

Clin Cosmet Investig Dermatol. 2017 Feb 23;10:67-69. doi: 10.2147/CCID.S127040. eCollection 2017.

Superficial basal cell carcinoma treated with 70% trichloroacetic acid applied topically: a case study.

Clinical, cosmetic and investigational dermatology

Anca Chiriac, Piotr Brzezinski, Cosmin Moldovan, Cristian Podoleanu, Marius Florin Coros, Simona Stolnicu

Affiliations

  1. Department of Dermatology, Nicolina Medical Center, Iasi; Department of Dermatology, Apollonia University, Iasi; Department of Dermatology, P. Poni Research Institute, Romanian Academy Iasi, Romania.
  2. Department of Dermatology, 6th Military Support Unit, Utska, Poland.
  3. Department of Histology.
  4. Department of Cardiology.
  5. Department of Surgery.
  6. Department of Pathology, University of Medicine and Pharmacy of Targu-Mures, Targu-Mures, Romania.

PMID: 28260938 PMCID: PMC5327847 DOI: 10.2147/CCID.S127040

Abstract

BACKGROUND: Basal cell carcinoma (BCC) is the most common form of skin cancer, affecting millions of people worldwide. The treatment concept for BCCs is the surgical one, but it is costly, as such, searching for alternative medical therapeutics is justified.

AIM: To highlight the efficacy of high concentration (70%) trichloroacetic acid (TCA) as a choice therapy for low-risk BCC.

METHOD AND PATIENT: Authors present, for the first time, the use of a high concentration TCA applied once a week for 2 consecutive weeks with a toothpick, on a patient with BCC on the right preauricular area.

RESULTS: On examination 4 weeks later, the lesion was not clinically and dermatoscopically evidenced.

CONCLUSION: High concentration TCA could be an effective and safe, non-invasive choice of therapy for low-risk BCC, easy to perform, not expensive, with good cosmetic results, especially for patients who are not likely to undergo invasive or expensive treatments.

Keywords: basal cell carcinoma; dermatology; therapy; trichloroacetic acid

Conflict of interest statement

Disclosure The authors declare no conflicts of interest in this work.

References

  1. J Anal Bioanal Tech. 2014 Sep;5(4):null - PubMed
  2. J Cosmet Dermatol. 2015 Sep;14(3):209-15 - PubMed
  3. Pan Afr Med J. 2016 Jun 22;24:157 - PubMed
  4. J Cutan Aesthet Surg. 2012 Oct;5(4):261-5 - PubMed
  5. J Natl Cancer Inst. 1996 Mar 20;88(6):349-54 - PubMed
  6. J Clin Aesthet Dermatol. 2012 Jun;5(6):25-36 - PubMed
  7. Br J Ophthalmol. 1999 Jan;83(1):85-8 - PubMed
  8. J Am Acad Dermatol. 2015 Aug;73(2):323-5 - PubMed
  9. Acta Derm Venereol. 2016 May;96(4):505-9 - PubMed
  10. Dermatol Surg. 2002 Nov;28(11):1017-21; discussion 1021 - PubMed
  11. Nat Clin Pract Oncol. 2007 Aug;4(8):462-9 - PubMed

Publication Types