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Front Immunol. 2017 Feb 27;8:197. doi: 10.3389/fimmu.2017.00197. eCollection 2017.

Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4.

Frontiers in immunology

Elena Muraro, Anna Merlo, Debora Martorelli, Michela Cangemi, Silvia Dalla Santa, Riccardo Dolcetti, Antonio Rosato

Affiliations

  1. Immunopathology and Cancer Biomarkers, Traslational Research Department, IRCCS, C.R.O. National Cancer Institute , Aviano, Pordenone , Italy.
  2. Department of Immunology and Blood Transfusions, San Bortolo Hospital , Vicenza , Italy.
  3. Istituto Oncologico Veneto IOV-IRCCS , Padova , Italy.
  4. Immunopathology and Cancer Biomarkers, Traslational Research Department, IRCCS, C.R.O. National Cancer Institute, Aviano, Pordenone, Italy; Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, QLD, Australia.
  5. Istituto Oncologico Veneto IOV-IRCCS, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, Oncology and Immunology Section, University of Padova, Padova, Italy.

PMID: 28289418 PMCID: PMC5327441 DOI: 10.3389/fimmu.2017.00197

Abstract

CD4

Keywords: CD4+ T cells; cytotoxicity; immunotherapy; viral infection; virus-driven tumors

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