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Ann Surg Treat Res. 2017 Mar;92(3):143-148. doi: 10.4174/astr.2017.92.3.143. Epub 2017 Feb 24.

The efficacy of laparoscopic cholecystectomy without discontinuation in patients on antithrombotic therapy.

Annals of surgical treatment and research

Jong Hyuk Yun, Hae Il Jung, Hyoung Uk Lee, Moo-Jun Baek, Sang Ho Bae

Affiliations

  1. Department of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.

PMID: 28289668 PMCID: PMC5344804 DOI: 10.4174/astr.2017.92.3.143

Abstract

PURPOSE: Laparoscopic cholecystectomy (LC) is one of the most commonly performed surgeries in the world today. However, there is no consensus regarding whether LC can be performed in patients with acute cholecystitis while on antithrombotic therapy. The objective of our study was to describe postoperative outcomes of patients who underwent emergent LC without interruption to antithrombotic therapy.

METHODS: We performed a retrospective review of patients who underwent LC for acute cholecystitis while on antithrombotic therapy from 2010 to 2015 at Soonchunhyang Universtiy Cheonan Hospital. Patients were divided into 2 groups as underwent emergent LC and elective LC.

RESULTS: A total of 67 patients (emergent group, 22; elective group, 45) were included in the analysis. Elective group had significantly longer duration between the admission and operation (8 [7-10] days

CONCLUSION: Emergent LC without interruption to antithrombotic therapy was relatively safe and useful. A well-designed multicenter study is needed to confirm the safety and efficacy of LC without suspension of antithrombotic therapy and to provide a simple guideline.

Keywords: Acute cholecystitis; Antithrombotic therapy; Laparoscopic cholecystectomy

Conflict of interest statement

CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.

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