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Rai H, Sinha N, Finn J, et al. Association of serum lipids and coronary artery disease with polymorphisms in the apolipoprotein AI-CIII-AIV gene cluster. Cogent Med. 2016;3(1):1266789doi: 10.1080/2331205X.2016.1266789.
Rai, H., Sinha, N., Finn, J., Agrawal, S., & Mastana, S. (2016). Association of serum lipids and coronary artery disease with polymorphisms in the apolipoprotein AI-CIII-AIV gene cluster. Cogent medicine, 3(1), 1266789. https://doi.org/10.1080/2331205X.2016.1266789
Rai, Himanshu, et al. "Association of serum lipids and coronary artery disease with polymorphisms in the apolipoprotein AI-CIII-AIV gene cluster." Cogent medicine vol. 3,1 (2016): 1266789. doi: https://doi.org/10.1080/2331205X.2016.1266789
Rai H, Sinha N, Finn J, Agrawal S, Mastana S. Association of serum lipids and coronary artery disease with polymorphisms in the apolipoprotein AI-CIII-AIV gene cluster. Cogent Med. 2016 Dec 31;3(1):1266789. doi: 10.1080/2331205X.2016.1266789. Epub 2016 Dec 17. PMID: 28261635; PMCID: PMC5314817.
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Cogent Med. 2016 Dec 31;3(1):1266789. doi: 10.1080/2331205X.2016.1266789. Epub 2016 Dec 17.

Association of serum lipids and coronary artery disease with polymorphisms in the apolipoprotein AI-CIII-AIV gene cluster.

Cogent medicine

Himanshu Rai, Nakul Sinha, James Finn, Suraksha Agrawal, Sarabjit Mastana

Affiliations

  1. Department of Cardiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , UP , India.
  2. Department of Cardiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India; Department of Cardiology, Sahara India Medical Institute, Lucknow, UP, India.
  3. Human Genomics Laboratory, School of Sport Exercise and Health Sciences, Loughborough University , Loughborough LE11 3TU , UK.
  4. Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , UP , India.

PMID: 28261635 PMCID: PMC5314817 DOI: 10.1080/2331205X.2016.1266789

Abstract

Genetic variants are considered as one of the main determinants of the concentration of serum lipids and coronary artery disease (CAD). Polymorphisms in the Apolipoprotein (Apo) AI-CIII-AIV gene cluster has been known to affect the concentrations of various lipid sub-fractions and the risk of CAD. The present study assessed associations between polymorphisms of the Apo AI-CIII-AIV gene cluster, [ApoA-I,-75G > A, (rs1799837); ApoC-III 3238C > G, (

Keywords: apolipoprotein (Apo) AI-CIII-AIV gene cluster; coronary artery disease (CAD); linkage disequilibrium, haplotypes; serum lipids; single nucleotide polymorphisms (SNPs)

Conflict of interest statement

Competing InterestsThe authors declare no competing interests.

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