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Ouanes S, Castelao E, von Gunten A, et al. Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study. Front Aging Neurosci. 2017;9:63doi: 10.3389/fnagi.2017.00063.
Ouanes, S., Castelao, E., von Gunten, A., Vidal, P. M., Preisig, M., & Popp, J. (2017). Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study. Frontiers in aging neuroscience, 963. https://doi.org/10.3389/fnagi.2017.00063
Ouanes, Sami, et al. "Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study." Frontiers in aging neuroscience vol. 9 (2017): 63. doi: https://doi.org/10.3389/fnagi.2017.00063
Ouanes S, Castelao E, von Gunten A, Vidal PM, Preisig M, Popp J. Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study. Front Aging Neurosci. 2017 Mar 14;9:63. doi: 10.3389/fnagi.2017.00063. eCollection 2017. PMID: 28352228; PMCID: PMC5348534.
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Front Aging Neurosci. 2017 Mar 14;9:63. doi: 10.3389/fnagi.2017.00063. eCollection 2017.

Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study.

Frontiers in aging neuroscience

Sami Ouanes, Enrique Castelao, Armin von Gunten, Pedro M Vidal, Martin Preisig, Julius Popp

Affiliations

  1. Department of Psychiatry, University Hospital of Lausanne Lausanne, Switzerland.
  2. Department of Internal Medicine, University Hospital of Lausanne Lausanne, Switzerland.

PMID: 28352228 PMCID: PMC5348534 DOI: 10.3389/fnagi.2017.00063

Abstract

Certain personality traits, in particular higher neuroticism, have been associated, on one hand, with elevated cortisol levels, and on the other hand, with poorer cognitive performance. At the same time, several studies highlighted the association between high cortisol and poor cognitive functioning. Here, we hypothesized that increased cortisol may be associated with poorer cognition and with certain personality traits (mainly high neuroticism), and that personality might explain the association between cortisol and cognition. A cross-sectional analysis was conducted using data from Colaus/PsyColaus, a population-based study involving residents of Lausanne, Switzerland. Salivary cortisol samples (upon waking, 30 min after waking, at 11 am and at 8 pm) along with cognitive and personality measures were obtained from 643 non-demented participants aged at least 65. Personality traits were assessed using the NEO Five-Factor Inventory (NEO-FFI). We examined the links between the cortisol Area under the Curve (AUC), the Clinical Dementia Rating Sum of Boxes (CDRSOB) and the NEO-FFI scores. No association was found between personality traits and the CDRSOB or the MMSE score, controlling for age, sex, depression, education and BMI. However, the executive functioning domain

Keywords: agreeableness; cognition; cortisol; dementia; memory; neuroticism; openness; personality

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