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Schneberger D, DeVasure JM, Bailey KL, et al. Effect of low-level CO. J Occup Med Toxicol. 2017;12:9doi: 10.1186/s12995-017-0155-8.
Schneberger, D., DeVasure, J. M., Bailey, K. L., Romberger, D. J., & Wyatt, T. A. (2017). Effect of low-level CO. Journal of occupational medicine and toxicology (London, England), 129. https://doi.org/10.1186/s12995-017-0155-8
Schneberger, David, et al. "Effect of low-level CO." Journal of occupational medicine and toxicology (London, England) vol. 12 (2017): 9. doi: https://doi.org/10.1186/s12995-017-0155-8
Schneberger D, DeVasure JM, Bailey KL, Romberger DJ, Wyatt TA. Effect of low-level CO. J Occup Med Toxicol. 2017 Mar 24;12:9. doi: 10.1186/s12995-017-0155-8. eCollection 2017. PMID: 28352288; PMCID: PMC5366145.
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J Occup Med Toxicol. 2017 Mar 24;12:9. doi: 10.1186/s12995-017-0155-8. eCollection 2017.

Effect of low-level CO.

Journal of occupational medicine and toxicology (London, England)

David Schneberger, Jane M DeVasure, Kristina L Bailey, Debra J Romberger, Todd A Wyatt

Affiliations

  1. Pulmonary, Critical Care, Sleep & Allergy Division, Department of Internal Medicine, University of Nebraska Medical Center, 985910 The Nebraska Medical Center, Omaha, NE 68198-5910 USA.
  2. Research Service, Veterans Administration Nebraska Western Iowa Health Care System, Omaha, NE 68105 USA.
  3. Department of Environmental, Agricultural and Occupational Health, University of Nebraska Medical Center, 985910 The Nebraska Medical Center, Omaha, NE 68198-5910 USA.

PMID: 28352288 PMCID: PMC5366145 DOI: 10.1186/s12995-017-0155-8

Abstract

BACKGROUND: Organic hog barn dust (HDE) exposure induces lung inflammation and long-term decreases in lung function in agricultural workers. While concentrations of common gasses in confined animal facilities are well characterized, few studies have been done addressing if exposure to elevated barn gasses impacts the lung immune response to organic dusts. Given the well documented effects of hypercapnia at much higher levels we hypothesized that CO

METHODS: Using a mouse model, C57BL/6 mice were nasally instilled with defined barn dust extracts and then housed in an exposure box maintained at one of several CO

RESULTS: Exposure to elevated CO

CONCLUSIONS: We show that even at mandated safe exposure limits, CO

Keywords: Barn dust; Carbon dioxide; Hypercapnia

References

  1. Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L657-65 - PubMed
  2. Environ Health Perspect. 2012 Dec;120(12):1671-7 - PubMed
  3. Chest. 2000 May;117(5):1488-95 - PubMed
  4. Am J Respir Crit Care Med. 1994 Dec;150(6 Pt 2):S160-4 - PubMed
  5. J Occup Environ Med. 2000 Mar;42(3):260-9 - PubMed
  6. Environ Monit Assess. 2013 Jan;185(1):59-72 - PubMed
  7. FASEB J. 2010 Jul;24(7):2178-90 - PubMed
  8. Am J Respir Cell Mol Biol. 2010 Jun;42(6):706-15 - PubMed
  9. J Inflamm. 1995;45(3):207-19 - PubMed
  10. J Occup Environ Med. 2006 Jul;48(7):741-8 - PubMed
  11. J Allergy Clin Immunol. 2007 Aug;120(2):366-73 - PubMed
  12. J Immunol. 1996 May 1;156(9):3102-6 - PubMed
  13. Am J Respir Cell Mol Biol. 2003 Jul;29(1):124-32 - PubMed
  14. J Agromedicine. 2002;8(2):57-76 - PubMed
  15. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1085-95 - PubMed
  16. J Appl Physiol (1985). 2002 Jul;93(1):289-96 - PubMed
  17. Am J Respir Cell Mol Biol. 1992 Aug;7(2):214-21 - PubMed
  18. Ann Occup Hyg. 2012 Nov;56(9):1080-90 - PubMed
  19. J Appl Physiol (1985). 2004 May;96(5):1738-44 - PubMed
  20. PLoS One. 2014 Apr 18;9(4):e95578 - PubMed
  21. Am J Respir Cell Mol Biol. 1996 Mar;14(3):288-95 - PubMed
  22. J Immunol. 2005 Jun 1;174(11):7341-51 - PubMed
  23. Toxicol Rev. 2005;24(4):229-35 - PubMed
  24. J Immunol. 1995 Dec 1;155(11):5352-8 - PubMed
  25. Am J Physiol Lung Cell Mol Physiol. 2010 Nov;299(5):L664-71 - PubMed
  26. J Toxicol Environ Health A. 2010;73(10):684-700 - PubMed
  27. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L388-99 - PubMed
  28. Am Ind Hyg Assoc J. 1985 Nov;46(11):658-61 - PubMed
  29. Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1049-54 - PubMed
  30. Cytokine. 2008 Oct;44(1):108-17 - PubMed
  31. J Toxicol Environ Health B Crit Rev. 2012;15(8):524-41 - PubMed
  32. J Agric Saf Health. 2003 Aug;9(3):185-96 - PubMed
  33. Chest. 1997 Jun;111(6):1733-41 - PubMed
  34. Am J Respir Crit Care Med. 2005 Jan 15;171(2):147-57 - PubMed
  35. J Allergy Clin Immunol. 2003 Feb;111(2 Suppl):S460-75 - PubMed
  36. Lancet. 1999 Oct 9;354(9186):1283-6 - PubMed
  37. Thorax. 1997 Jul;52(7):638-42 - PubMed
  38. Toxicol Appl Pharmacol. 1994 Mar;125(1):17-26 - PubMed
  39. Environ Health Perspect. 2005 May;113(5):567-76 - PubMed
  40. Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1163-70 - PubMed
  41. Curr Opin Allergy Clin Immunol. 2012 Apr;12(2):126-32 - PubMed
  42. Int Immunopharmacol. 2015 Jul;27(1):76-84 - PubMed
  43. Exp Lung Res. 2008 Jan;34(1):19-35 - PubMed

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