Open Med (Wars). 2015 Dec 17;10(1):538-542. doi: 10.1515/med-2015-0091. eCollection 2015.
Tailored treatment of intestinal angiodysplasia in elderly.
Open medicine (Warsaw, Poland)
Rita Compagna, Raffaele Serra, Luigi Sivero, Gennaro Quarto, Gabriele Vigliotti, Tommaso Bianco, Aldo Rocca, Maurizio Amato, Michele Danzi, Ermenegildo Furino, Marco Milone, Bruno Amato
Affiliations
Affiliations
- Department of Clinical Medicine and Surgery, University of Naples "Federico II" Via S. Pansini,5 - 80131 Napoli, Italy ; Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro. Catanzaro, Italy .; Interuniversity Center of Phlebolymphology (CIFL). International Research and Educational Program in Clinical and Experimental Biotechnology. Headquarters: University Magna Graecia of Catanzaro, Catanzaro, Italy.
- Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro. Catanzaro, Italy ; Interuniversity Center of Phlebolymphology (CIFL). International Research and Educational Program in Clinical and Experimental Biotechnology. Headquarters: University Magna Graecia of Catanzaro, Catanzaro, Italy.
- Department of Clinical Medicine and Surgery, University of Naples "Federico II" Via S. Pansini,5 - 80131 Napoli, Italy.
- Department of Clinical Medicine and Surgery, University of Naples "Federico II" Via S. Pansini,5 - 80131 Napoli, Italy . Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro. Catanzaro, Italy ; Interuniversity Center of Phlebolymphology (CIFL). International Research and Educational Program in Clinical and Experimental Biotechnology. Headquarters: University Magna Graecia of Catanzaro, Catanzaro, Italy.
PMID: 28352751
PMCID: PMC5368880 DOI: 10.1515/med-2015-0091
Abstract
BACKGROUND: Angiodysplasia of the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and severe anemia in elderly. Different treatments exist for this kind of pathology.
METHODS: The aim of this work was to study 40 patients treated for intestinal angiodysplasia with two different kind of endoscopic treatments: argon plasma coagulation (APC) and bipolar electrocoagulation (BEC).
RESULTS: Age of patients was similar in both groups (76,2 ± 10.8 years vs 74,8 ± 8,7 years, P = 0,005). Angiodysplasia treated were located in small bowel, right colon, left colon, transverse colon and cecum. We analysed number of treatment, recurrence, hospital discharge, needs of blood transfusions before and after endoscopic treatment. Number of treatment was the same in both groups (1,2 ± 0,2 vs 1,1 ± 0,1, P < 0,001). We had more recurrence in patients treated with BEC (4/20 vs 2/20, P < 0,001). Hospital discharge was comparable in both groups (5,3 ± 3,1 days vs 5,4 ± 2,8 years, P < 0.001).
CONCLUSIONS: Treatment of angiodysplasia in elderly is not easy. Different kinds of treatment could be adopted. APC and BEC are both safe and effective. The choice of a treatment should consider several factors: age, comorbidity, source of bleeding. In conclusion we think that treatment of bleeding for angiodysplasia in elder population should be a tailored treatment.
Keywords: Angiodysplasia; Argon plasma coagulation; Bleeding; Elderly; Tailored
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