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Open Med (Wars). 2016 Jun 23;11(1):106-114. doi: 10.1515/med-2016-0021. eCollection 2016.

Prevention and treatment of peritoneal adhesions in patients affected by vascular diseases following surgery: a review of the literature.

Open medicine (Warsaw, Poland)

Aldo Rocca, Giovanni Aprea, Giuseppe Surfaro, Maurizio Amato, Antonio Giuliani, Marianna Paccone, Andrea Salzano, Anna Russo, Domenico Tafuri, Bruno Amato

Affiliations

  1. Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy . Via Sergio Pansini, 80131 Naples, Italy.
  2. Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
  3. Unit of Surgery, A. Cardarelli Hospital, Campo-basso, Italy.
  4. Unit of Hepatobiliary Surgery and Liver Transplant Center, Department of Gastroenterology and Transplantation, "A. Cardarelli" Hospital, Naples, Italy.
  5. Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
  6. Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  7. Santa Maria delle Grazie Hospital, Pathology Unit, Pozzuoli, Naples, Italy.
  8. Department of Sport Sciences and Wellness, University of Naples "Parthenope", Naples, Italy.

PMID: 28352777 PMCID: PMC5329808 DOI: 10.1515/med-2016-0021

Abstract

Intra-abdominal adhesions are the most frequently occurring postoperative complication following abdomino-pelvic surgery. Abdominal and pelvic surgery can lead to peritoneal adhesion formation causing infertility, chronic pelvic pain, and intestinal obstruction. Laparoscopy today is considered the gold standard of care in the treatment of several abdominal pathologies as well as in a wide range of vascular diseases. Laparoscopy has several advantages in comparison to open surgery. These include rapid recovery times, shorter hospitalisation, reduced postoperative pain, as well as cosmetic benefits. The technological improvements in this particular surgical field along with the development of modern techniques and the acquisition of specific laparoscopic skills have allowed for its wider utilization in operations with fully intracorporeal anastomoses. Postoperative adhesions are caused by aberrant peritoneal healing and are the leading cause of postoperative bowel obstruction. The use of anti-adherence barriers is currently being advocated for their prevention. The outcome of the investigation showed adhesion formation inhibition without direct detrimental effects on anastomotic healing. Poor anasto-motic healing can provoke adhesions even in the presence of anti-adhesion barriers. This review gives a short overview on the current evidence on the pathophysiology and prevention of peritoneal adhesions.

Keywords: Anti-adhesive barriers; Laparoscopy; Pain; Peritoneal adhesions; Vascular Surgery

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