15 cm. Surgical treatment is the best choice for both benign and malignant neoplasms. We retrospectively analyzed the main case series of giant fibrous tumors of the pleura. In addition we report our experience of a 76-year-old woman treated by pre-surgical embolization involving implantation of vascular plugs. Surgery was successfully carried out without complications; imaging and functional assessment 6 months post intervention demonstrated both the absence of recurrence and improvement of lung function parameters." />
Display options
Cite
Perrotta F, Cerqua FS, Cammarata A, et al. Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature. Open Med (Wars). 2016;11(1):220-225doi: 10.1515/med-2016-0042.
Perrotta, F., Cerqua, F. S., Cammarata, A., Izzo, A., Bergaminelli, C., Curcio, C., Guarino, C., Grella, E., Forzano, I., Cennamo, A., Tafuri, D., Rocca, A., Bianco, A., & Mazzarella, G. (2016). Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature. Open medicine (Warsaw, Poland), 11(1), 220-225. https://doi.org/10.1515/med-2016-0042
Perrotta, Fabio, et al. "Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature." Open medicine (Warsaw, Poland) vol. 11,1 (2016): 220-225. doi: https://doi.org/10.1515/med-2016-0042
Perrotta F, Cerqua FS, Cammarata A, Izzo A, Bergaminelli C, Curcio C, Guarino C, Grella E, Forzano I, Cennamo A, Tafuri D, Rocca A, Bianco A, Mazzarella G. Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature. Open Med (Wars). 2016 Jun 23;11(1):220-225. doi: 10.1515/med-2016-0042. eCollection 2016. PMID: 28352798; PMCID: PMC5329829.
Copy Download .nbib Format: NLM
Share it on

Open Med (Wars). 2016 Jun 23;11(1):220-225. doi: 10.1515/med-2016-0042. eCollection 2016.

Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature.

Open medicine (Warsaw, Poland)

Fabio Perrotta, Francesco Saverio Cerqua, Antonino Cammarata, Alessandro Izzo, Carlo Bergaminelli, Carlo Curcio, Carmine Guarino, Edoardo Grella, Imma Forzano, Antonio Cennamo, Domenico Tafuri, Aldo Rocca, Andrea Bianco, Gennaro Mazzarella

Affiliations

  1. Department of Cardiotho-racic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
  2. Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Naples, Italy.
  3. A.O. dei Colli - Hosp. Monaldi - Thoracic Surgery Unit, Naples, Italy.
  4. A.O. dei Colli - Hosp. Monaldi - Bronchology Unit, Naples, Italy.
  5. Department of Sport Sciences and Wellness, University of Naples "Parthenope", Naples, Italy.
  6. Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.

PMID: 28352798 PMCID: PMC5329829 DOI: 10.1515/med-2016-0042

Abstract

The fibrous tumors of the pleura are rare primary tumors, accounting for 5% of malignant pleural neoplasms, which generally originate from sub-mesothelial mesenchymal tissue of the visceral pleura. These tumours generally exhibit clinical benign behavior although 12% of solitary fibrous tumors can be malignant and have worse outcomes. These tumors are considered "giant" when the lesion > 15 cm. Surgical treatment is the best choice for both benign and malignant neoplasms. We retrospectively analyzed the main case series of giant fibrous tumors of the pleura. In addition we report our experience of a 76-year-old woman treated by pre-surgical embolization involving implantation of vascular plugs. Surgery was successfully carried out without complications; imaging and functional assessment 6 months post intervention demonstrated both the absence of recurrence and improvement of lung function parameters.

Keywords: Embolization; Giant tumors; Solitary fibrous tumor of the pleura (SFTP); Surgical treatment

References

  1. Med Sci Monit. 2013 Feb 07;19:95-101 - PubMed
  2. Int J Mol Sci. 2014 Oct 29;15(11):19700-28 - PubMed
  3. J Cardiovasc Surg (Torino). 2000 Dec;41(6):945-52 - PubMed
  4. Rozhl Chir. 2010 Dec;89(12):750-3 - PubMed
  5. BMC Surg. 2013;13 Suppl 2:S46 - PubMed
  6. Front Cell Neurosci. 2015 Apr 24;9:153 - PubMed
  7. Int J Biochem Cell Biol. 2013 Jun;45(6):1145-53 - PubMed
  8. Am J Case Rep. 2013 Apr 02;14:91-3 - PubMed
  9. Environ Pollut. 2012 Dec;171:162-7 - PubMed
  10. Lung India. 2012 Apr;29(2):179-81 - PubMed
  11. J Clin Oncol. 1999 May;17(5):1526-34 - PubMed
  12. Ann Thorac Surg. 2002 Jul;74(1):285-93 - PubMed
  13. Curr Vasc Pharmacol. 2014 Jan;12 (1):87-105 - PubMed
  14. Ann Thorac Surg. 2013 Jul;96(1):319-21 - PubMed
  15. Radiographics. 2003 May-Jun;23(3):759-83 - PubMed
  16. Respir Res. 2015 Jun 24;16:74 - PubMed
  17. Int J Mol Sci. 2013 Jun 17;14(6):12696-713 - PubMed
  18. Stem Cells Dev. 2013 Oct 1;22(19):2561-80 - PubMed
  19. Curr Protein Pept Sci. 2015;16(3):182-7 - PubMed
  20. Ann Thorac Surg. 2000 Mar;69(3):937-9 - PubMed
  21. Stem Cells. 2011 Nov;29(11):1898-907 - PubMed
  22. Int J Surg. 2014;12 Suppl 2:S73-7 - PubMed
  23. In Vivo. 2014 Jul-Aug;28(4):557-61 - PubMed
  24. J Pathol. 2002 Oct;198(2):252-7 - PubMed
  25. Cell Calcium. 2015 Feb;57(2):89-100 - PubMed
  26. Ann Thorac Surg. 2002 Mar;73(3):983-5 - PubMed
  27. Clin Imaging. 2013 May-Jun;37(3):598-601 - PubMed
  28. Monaldi Arch Chest Dis. 2002 Jun-Aug;57(3-4):196-9 - PubMed
  29. Curr Med Chem. 2012;19(34):5802-18 - PubMed
  30. Respir Med. 2007 Jun;101(6):1155-62 - PubMed
  31. Eur J Cardiothorac Surg. 2001 Feb;19(2):185-9 - PubMed
  32. Tumour Biol. 2015 Sep;36(9):6603-14 - PubMed
  33. Cir Cir. 2010 Jan-Feb;78(1):31-43 - PubMed
  34. Biomed Res Int. 2014;2014:739494 - PubMed
  35. J Cell Physiol. 2016 Feb;231(2):314-27 - PubMed
  36. Environ Pollut. 2012 Feb;161:64-9 - PubMed
  37. Cancer Chemother Pharmacol. 2008 Apr;61(5):803-7 - PubMed
  38. Biomed Res Int. 2014;2014:658913 - PubMed
  39. Lung India. 2013 Jan;30(1):82-5 - PubMed
  40. World J Surg. 2010 Nov;34(11):2553-7 - PubMed
  41. Exp Hematol. 2015 Dec;43(12):1019-1030.e3 - PubMed
  42. PLoS One. 2012;7(9):e42541 - PubMed
  43. Anticancer Res. 2015 May;35(5):2769-74 - PubMed
  44. Lung Cancer. 2001 Dec;34 Suppl 4:S65-9 - PubMed
  45. Interact Cardiovasc Thorac Surg. 2011 Jun;12(6):1065 - PubMed
  46. AJR Am J Roentgenol. 2011 Mar;196(3):487-95 - PubMed
  47. PLoS One. 2014 Mar 06;9(3):e91099 - PubMed
  48. Stem Cells Dev. 2016 Feb 15;25(4):301-19 - PubMed
  49. Br J Cancer. 1996 Dec;74(11):1805-11 - PubMed
  50. J Clin Oncol. 2000 Jul;18(13):2529-36 - PubMed
  51. J Biol Regul Homeost Agents. 2010 Oct-Dec;24(4):425-32 - PubMed
  52. Allergy. 2000;55 Suppl 61:6-9 - PubMed

Publication Types