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Khan ST, Khan M, Ahmad J, et al. Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans. AMB Express. 2017;7(1):49doi: 10.1186/s13568-017-0344-y.
Khan, S. T., Khan, M., Ahmad, J., Wahab, R., Abd-Elkader, O. H., Musarrat, J., Alkhathlan, H. Z., & Al-Kedhairy, A. A. (2017). Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans. AMB Express, 7(1), 49. https://doi.org/10.1186/s13568-017-0344-y
Khan, Shams Tabrez, et al. "Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans." AMB Express vol. 7,1 (2017): 49. doi: https://doi.org/10.1186/s13568-017-0344-y
Khan ST, Khan M, Ahmad J, Wahab R, Abd-Elkader OH, Musarrat J, Alkhathlan HZ, Al-Kedhairy AA. Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans. AMB Express. 2017 Dec;7(1):49. doi: 10.1186/s13568-017-0344-y. Epub 2017 Feb 23. PMID: 28233286; PMCID: PMC5323333.
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AMB Express. 2017 Dec;7(1):49. doi: 10.1186/s13568-017-0344-y. Epub 2017 Feb 23.

Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans.

AMB Express

Shams Tabrez Khan, Merajuddin Khan, Javed Ahmad, Rizwan Wahab, Omar H Abd-Elkader, Javed Musarrat, Hamad Z Alkhathlan, Abdulaziz A Al-Kedhairy

Affiliations

  1. Zoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. [email protected].
  2. DNA Research Chair, Zoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. [email protected].
  3. Department of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
  4. Zoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
  5. DNA Research Chair, Zoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
  6. Department of Ag. Microbiology, Faculty of Agricultural Sciences, AMU, Aligarh, 202002, India.
  7. Department of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. [email protected].

PMID: 28233286 PMCID: PMC5323333 DOI: 10.1186/s13568-017-0344-y

Abstract

Organic compounds from plants are an attractive alternative to conventional antimicrobial agents. Therefore, two compounds namely M-1 and M-2 were purified from Origanum vulgare L. and were identified as carvacrol and thymol, respectively. Antimicrobial and antibiofilm activities of these compounds along with chlorhexidine digluconate using various assays was determined against dental caries causing bacteria Streptococcus mutans. The IC

Keywords: Alternative antimicrobials; Carvacrol; Oral hygiene; S. mutans; Thymol

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