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Barnett R, Raszkowski D, Winckler T, et al. Versatile synthesis of the signaling peptide glorin. Beilstein J Org Chem. 2017;13:247-250doi: 10.3762/bjoc.13.27.
Barnett, R., Raszkowski, D., Winckler, T., & Stallforth, P. (2017). Versatile synthesis of the signaling peptide glorin. Beilstein journal of organic chemistry, 13247-250. https://doi.org/10.3762/bjoc.13.27
Barnett, Robert, et al. "Versatile synthesis of the signaling peptide glorin." Beilstein journal of organic chemistry vol. 13 (2017): 247-250. doi: https://doi.org/10.3762/bjoc.13.27
Barnett R, Raszkowski D, Winckler T, Stallforth P. Versatile synthesis of the signaling peptide glorin. Beilstein J Org Chem. 2017 Feb 08;13:247-250. doi: 10.3762/bjoc.13.27. eCollection 2017. PMID: 28326133; PMCID: PMC5331329.
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Beilstein J Org Chem. 2017 Feb 08;13:247-250. doi: 10.3762/bjoc.13.27. eCollection 2017.

Versatile synthesis of the signaling peptide glorin.

Beilstein journal of organic chemistry

Robert Barnett, Daniel Raszkowski, Thomas Winckler, Pierre Stallforth

Affiliations

  1. Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute - HKI, Junior Research Group Chemistry of Microbial Communication, Beutenbergstr. 11, D-07745 Jena, Germany.
  2. Faculty of Biology and Pharmacy, Institute of Pharmacy, Department of Pharmaceutical Biology, University of Jena, Semmelweisstrasse 10, D-07743 Jena, Germany.

PMID: 28326133 PMCID: PMC5331329 DOI: 10.3762/bjoc.13.27

Abstract

We present a versatile synthesis of the eukaryotic signaling peptide glorin as well as glorinamide, a synthetic analog. The ability of these compounds to activate glorin-induced genes in the social amoeba

Keywords: Dictyostelium; Polysphondylium; glorin; multicellularity; signaling molecules; social amoebae

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