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Betensky M, Bittles MA, Colombani P, et al. How We Manage Pediatric Deep Venous Thrombosis. Semin Intervent Radiol. 2017;34(1):35-49doi: 10.1055/s-0036-1597762.
Betensky, M., Bittles, M. A., Colombani, P., & Goldenberg, N. A. (2017). How We Manage Pediatric Deep Venous Thrombosis. Seminars in interventional radiology, 34(1), 35-49. https://doi.org/10.1055/s-0036-1597762
Betensky, Marisol, et al. "How We Manage Pediatric Deep Venous Thrombosis." Seminars in interventional radiology vol. 34,1 (2017): 35-49. doi: https://doi.org/10.1055/s-0036-1597762
Betensky M, Bittles MA, Colombani P, Goldenberg NA. How We Manage Pediatric Deep Venous Thrombosis. Semin Intervent Radiol. 2017 Mar;34(1):35-49. doi: 10.1055/s-0036-1597762. PMID: 28265128; PMCID: PMC5334487.
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Semin Intervent Radiol. 2017 Mar;34(1):35-49. doi: 10.1055/s-0036-1597762.

How We Manage Pediatric Deep Venous Thrombosis.

Seminars in interventional radiology

Marisol Betensky, Mark A Bittles, Paul Colombani, Neil A Goldenberg

Affiliations

  1. Pediatric Thrombosis Program, Johns Hopkins All Children's Hospital, St. Petersburg, Florida; Division of Hematology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  2. Department of Radiology, Johns Hopkins All Children's Hospital, St. Petersburg, Florida.
  3. Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Surgery, Johns Hopkins All Children's Hospital, St. Petersburg, Florida.

PMID: 28265128 PMCID: PMC5334487 DOI: 10.1055/s-0036-1597762

Abstract

Over the past two decades, the incidence and recognition of venous thromboembolism (VTE) in children has significantly increased, likely as a result of improvements in the medical care of critically ill patients and increased awareness of thrombotic complications among medical providers. Current recommendations for the management of VTE in children are largely based on data from pediatric registries and observational studies, or extrapolated from adult data. The scarcity of high-quality evidence-based recommendations has resulted in marked variations in the management of pediatric VTE among providers. The purpose of this article is to summarize our institutional approach for the management of VTE in children based on available evidence, guidelines, and clinical practice considerations. Therapeutic strategies reviewed in this article include the use of conventional anticoagulants, parenteral targeted anticoagulants, new direct oral anticoagulants, thrombolysis, and mechanical approaches for the management of pediatric VTE.

Keywords: anticoagulants; pediatric; thrombolytic therapy; venous thromboembolism

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