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Leite LI, Leite GO, Fernandes Silva BA, et al. Antinociceptive action of . Avicenna J Phytomed. 2017;7(1):93-98
Leite, L. I., Leite, G. O., Fernandes Silva, B. A., Gonçalves Sousa, S. D., Coutinho, T. S., Sampaio, R. S., Menezes, I., Martins Costa, J. G., & Campos, A. R. (2017). Antinociceptive action of . Avicenna journal of phytomedicine, 7(1), 93-98.
Leite, Laura Inocencio, et al. "Antinociceptive action of ." Avicenna journal of phytomedicine vol. 7,1 (2017): 93-98.
Leite LI, Leite GO, Fernandes Silva BA, Gonçalves Sousa SD, Coutinho TS, Sampaio RS, Menezes I, Martins Costa JG, Campos AR. Antinociceptive action of . Avicenna J Phytomed. 2017 Jan-Feb;7(1):93-98. PMID: 28265551; PMCID: PMC5329181.
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Avicenna J Phytomed. 2017 Jan-Feb;7(1):93-98.

Antinociceptive action of .

Avicenna journal of phytomedicine

Laura Inocencio Leite, Gerlânia de Oliveira Leite, Bruno Anderson Fernandes Silva, Severino Denício Gonçalves Sousa, Thales Silva Coutinho, Renata Souza Sampaio, Irwin Menezes, José Galberto Martins Costa, Adriana Rolim Campos

Affiliations

  1. Department of Biology at the Federal University of Cariri, Brejo Santo - CE, Brazil.
  2. Department of Pharmacology, University of Santa Maria, Santa Maria- RS, Brazil.
  3. Department of Chemical Biological at the Regional University of Cariri, Crato - CE, Brazil.
  4. Department of Pharmacology at the University of Fortaleza, Fortaleza - CE, Brazil.

PMID: 28265551 PMCID: PMC5329181

Abstract

MATERIALS AND METHODS: The antinociceptive activity was assessed using the capsaicin, glutamate, hot plate and cold allodynia tests. The antipuritic effects were also verified based on histamine-induced scratching behavior.

RESULTS: EOVA reduced the paw licking induced by capsaicin, but not that induced by glutamate. The essential oil increased the latency time in the hot plate, attenuated the cold allodynia induced by acetone and inhibited histamine-induced scratching behavior.

CONCLUSION: The experimental data demonstrated that EOVA showed central and peripheral antinociceptive activity and antipruritic effect.

Keywords: Antinociceptive; Antipruritic; Essential oil; Vanillosmopsisarborea

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