Allergy Asthma Immunol Res. 2017 May;9(3):212-219. doi: 10.4168/aair.2017.9.3.212.
Prevalence and Risk Factors of Urticaria With a Focus on Chronic Urticaria in Children.
Allergy, asthma & immunology research
Seung Jin Lee, Eun Kyo Ha, Hye Mi Jee, Kyung Suk Lee, Seung Won Lee, Mi Ae Kim, Dong Hyun Kim, Young Ho Jung, Youn Ho Sheen, Myong Soon Sung, Man Yong Han
Affiliations
Affiliations
- Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea.
- CHA University School of Medicine, Seongnam, Korea.
- Department of Allergy & Clinical Immunology, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea.
- Department of Dermatology, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea.
- Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea.
- Department of Pediatrics, CHA Gumi Medical Center, CHA University School of Medicine, Gumi, Korea.
- Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea. [email protected].
PMID: 28293927
PMCID: PMC5352572 DOI: 10.4168/aair.2017.9.3.212
Abstract
PURPOSE: Limited data is available on the prevalence and risk factors of acute and chronic urticaria in children. Our purpose was to determine the prevalence and identify the risk factors of acute and chronic urticaria in Korean children.
METHODS: This population-based study examined 4,076 children (age 4 to 13 years) who were enrolled in the 2015 prospective Seongnam Atopy Project (SAP 2015) in Korea. The parents completed an urticaria questionnaire that included questions regarding the duration, severity, and triggering factors of urticaria. Blood sampling (n=464) was performed to measure vitamin D, total eosinophil count (TEC), and total IgE levels, and skin prick tests (n=503) were done.
RESULTS: The prevalences of the life-time, acute, and chronic urticaria were 22.5%, 13.9%, and 1.8% (chronic continuous urticaria, 0.7%; and chronic recurrent urticaria, 1.1%), respectively. Acute urticaria was significantly associated with allergic diseases and parental history of allergy (P<0.001), but chronic urticaria was not associated with these clinical factors. There was no significant difference in the 25-hydroxyvitamin D level between subjects with chronic urticaria and controls (P=0.124). Chronic continuous urticaria was associated with living in a new residence (aOR=2.38, 95% CI=1.02-5.54, P=0.044) and belonging to a family with a high income (aOR=4.24, 95% CI=1.24-14.56, P=0.022).
CONCLUSIONS: A total of 1.8% of children were found to have chronic urticaria. Living in a new residence and belonging to a family with a high income increased the risk of chronic continuous urticaria.
Copyright © 2017 The Korean Academy of Asthma, Allergy and Clinical Immunology · The Korean Academy of Pediatric Allergy and Respiratory Disease
Keywords: Acute urticarial; chronic urticarial; prevalence; risk factor, urticaria
Conflict of interest statement
There are no financial or other issues that might lead to conflict of interest.
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