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Figarella K, Marsiccobetre S, Arocha I, et al. Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca. Microb Cell. 2015;3(1):14-28doi: 10.15698/mic2016.01.471.
Figarella, K., Marsiccobetre, S., Arocha, I., Colina, W., Hasegawa, M., Rodriguez, M., Rodriguez-Acosta, A., Duszenko, M., Benaim, G., & Uzcategui, N. L. (2015). Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca. Microbial cell (Graz, Austria), 3(1), 14-28. https://doi.org/10.15698/mic2016.01.471
Figarella, K, et al. "Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca." Microbial cell (Graz, Austria) vol. 3,1 (2015): 14-28. doi: https://doi.org/10.15698/mic2016.01.471
Figarella K, Marsiccobetre S, Arocha I, Colina W, Hasegawa M, Rodriguez M, Rodriguez-Acosta A, Duszenko M, Benaim G, Uzcategui NL. Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca. Microb Cell. 2015 Dec 11;3(1):14-28. doi: 10.15698/mic2016.01.471. PMID: 28357313; PMCID: PMC5354587.
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Microb Cell. 2015 Dec 11;3(1):14-28. doi: 10.15698/mic2016.01.471.

Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca.

Microbial cell (Graz, Austria)

K Figarella, S Marsiccobetre, I Arocha, W Colina, M Hasegawa, M Rodriguez, A Rodriguez-Acosta, M Duszenko, G Benaim, N L Uzcategui

Affiliations

  1. Laboratory of Genomics and Proteomics, Biotechnology Center, IDEA Foundation. Caracas, Venezuela.
  2. Laboratory of Natural Products, School of Chemistry, Central University of Venezuela, Venezuela.
  3. Laboratory of Immunochemistry and Ultrastructure, Institute for Anatomy, Central University of Venezuela, Venezuela.
  4. Laboratory of Molecular Parasitology, Interfaculty Institute for Biochemistry, Tuebingen University, Germany.
  5. Laboratorio de Señalización Celular y Bioquímica de Parásitos, Instituto de Estudios Avanzados (IDEA) and Instituto de Biología Experimental, Facultad de Ciencias. Universidad Central de Venezuela, Caracas, Venezuela.

PMID: 28357313 PMCID: PMC5354587 DOI: 10.15698/mic2016.01.471

Abstract

The protozoan parasite

Keywords: Ca2+; Leishmania; ROS; autophagy; azoles; cell death; ergosterol

Conflict of interest statement

Conflict of interest: The authors declare no conflict of interest.

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