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Gosteva EV, Vasileva LV. [Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure Profile in Elderly Patients With Arterial Hypertension]. Kardiologiia. 2015;55(2):32-36
Gosteva, E. V., & Vasileva, L. V. (2015). [Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure Profile in Elderly Patients With Arterial Hypertension]. Kardiologiia, 55(2), 32-36.
Gosteva, E V, and Vasileva, L V. "[Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure Profile in Elderly Patients With Arterial Hypertension]." Kardiologiia vol. 55,2 (2015): 32-36.
Gosteva EV, Vasileva LV. [Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure Profile in Elderly Patients With Arterial Hypertension]. Kardiologiia. 2015 Feb;55(2):32-36. Russian. PMID: 28294808.
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Kardiologiia. 2015 Feb;55(2):32-36.

[Effect of Fixed Lercanidipine/Enalapril Combination on 24-Hour Blood Pressure Profile in Elderly Patients With Arterial Hypertension].

Kardiologiia

[Article in Russian]
E V Gosteva, L V Vasileva

Affiliations

  1. Voronezh State Medical Academy named after N.N. Burdenko of the Ministry of Public Health of the Russian Federation, Studencheskaya St., 394036 Voronezh, Russia.

PMID: 28294808

Abstract

We studied effect of therapy with fixed combination of lercanidipine and enalapril on 24-hour blood pressure (BP) profile in 34 elderly patients (mean age 76.4+/-5.2 years, 14 men, 20 women) with degree II hypertension. After clinical examination patients were given lercanidipine/enalapril combination (10/10 mg/day). The dose was increased to 10+20 mg/day when necessary. Assessment of efficacy was conducted on Rate of achievement of target BP [systolic (S) BP <150 mm HG, diastolic (D) BP<90 mmHg] and dynamics of parameters of 24-hour BP profile. Re-examinations were carried out on weeks 4.8 and 12 of treatment. Administration of lercanidipine/enalapril combination was associated with mean 24-hour SBP and DBP lowering (by15.3 and 8.7%, respectively). Diurnal and nocturnal SBP/DBP decreased by 15.7/ 9.2.

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