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Bozkurt Zincir S, Zincir S, Kabak SG. Remission of Episodic Sweating Attacks and Comorbid Depression in Shapiro Syndrome: Case Report. Noro Psikiyatr Ars. 2014;51(4):405-407doi: 10.5152/npa.2014.6996.
Bozkurt Zincir, S., Zincir, S., & Kabak, S. G. (2014). Remission of Episodic Sweating Attacks and Comorbid Depression in Shapiro Syndrome: Case Report. Noro psikiyatri arsivi, 51(4), 405-407. https://doi.org/10.5152/npa.2014.6996
Bozkurt Zincir, Selma, et al. "Remission of Episodic Sweating Attacks and Comorbid Depression in Shapiro Syndrome: Case Report." Noro psikiyatri arsivi vol. 51,4 (2014): 405-407. doi: https://doi.org/10.5152/npa.2014.6996
Bozkurt Zincir S, Zincir S, Kabak SG. Remission of Episodic Sweating Attacks and Comorbid Depression in Shapiro Syndrome: Case Report. Noro Psikiyatr Ars. 2014 Dec;51(4):405-407. doi: 10.5152/npa.2014.6996. Epub 2014 Dec 01. PMID: 28360663; PMCID: PMC5353179.
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Noro Psikiyatr Ars. 2014 Dec;51(4):405-407. doi: 10.5152/npa.2014.6996. Epub 2014 Dec 01.

Remission of Episodic Sweating Attacks and Comorbid Depression in Shapiro Syndrome: Case Report.

Noro psikiyatri arsivi

Selma Bozkurt Zincir, Serkan Zincir, Sevgi Gül Kabak

Affiliations

  1. Clinic of Psychiatry, Erenköy Psychiatric Training and Research Hospital, ?stanbul, Turkey.
  2. Clinic of Psychiatry, Gölcük Military Hospital, ?stanbul, Turkey.

PMID: 28360663 PMCID: PMC5353179 DOI: 10.5152/npa.2014.6996

Abstract

Shapiro syndrome, a rare disorder originally described by Shapiro and Plum in 1967, is characterized by episodic hypothermia and hyperhydrosis associated with agenesis of the corpus callosum. Proposed hypotheses to explain the clinical features of this syndrome include changes in the set point of the hypothalamic thermostat, increased norepinephrine (NE) release, and decreased plasma NE clearance. It was emphasized that the recognition of Shapiro syndrome in the evaluation of episodic hyperhydrosis is important. Here, we described a case with Shapiro syndrome who presented to our psychiatry clinic with recurrent episodic profuse sweating and depression. Sweating attacks and depression remitted after successful treatment with amitriptyline.

Keywords: Shapiro syndrome; corpus callosum agenesis; hyperhydrosis

Conflict of interest statement

Conflict of Interest: The authors reported no conflict of interest related to this article.

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