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Luo H, Yang S, Hong D, et al. Synthesis and in vitro antitumor activity of (1. Chem Cent J. 2017;11:23doi: 10.1186/s13065-017-0253-9.
Luo, H., Yang, S., Hong, D., Xue, W., & Xie, P. (2017). Synthesis and in vitro antitumor activity of (1. Chemistry Central journal, 1123. https://doi.org/10.1186/s13065-017-0253-9
Luo, Hui, et al. "Synthesis and in vitro antitumor activity of (1." Chemistry Central journal vol. 11 (2017): 23. doi: https://doi.org/10.1186/s13065-017-0253-9
Luo H, Yang S, Hong D, Xue W, Xie P. Synthesis and in vitro antitumor activity of (1. Chem Cent J. 2017 Mar 15;11:23. doi: 10.1186/s13065-017-0253-9. eCollection 2017. PMID: 28360932; PMCID: PMC5352699.
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Chem Cent J. 2017 Mar 15;11:23. doi: 10.1186/s13065-017-0253-9. eCollection 2017.

Synthesis and in vitro antitumor activity of (1.

Chemistry Central journal

Hui Luo, Shengjie Yang, Da Hong, Wei Xue, Pu Xie

Affiliations

  1. Guizhou Fruit Institute, Guizhou Academy of Agricultural Sciences, Guiyang, 550006 P. R. China.
  2. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, 550025 P. R. China.
  3. Ctr for R&D of Fine Chemicals, Guizhou University, Guiyang, 550025 P. R. China.
  4. R&D Center, Sinphar Tian-Li Pharmaceutical Co., Ltd, Hangzhou, 311100 P. R. China.

PMID: 28360932 PMCID: PMC5352699 DOI: 10.1186/s13065-017-0253-9

Abstract

BACKGROUND: Cancer is one of the leading causes of death and only second to heart diseases. Recently, preclinical studies have demonstrated that curcumin had a number of anticancer properties. Thus, we planned to synthesize a series of curcumin analogs to assess their antiproliferation efficacy.

RESULTS: A series of (1

CONCLUSIONS: This study suggests that most of the derivatives could inhibit the growth of human cancer cell lines. In addition, compound

Keywords: Antitumor activity; Apoptosis; Asymmetric curcumin analogs; MGC-803; Quinazoline derivatives of curcumin; Synthesis

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