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Vijayakumar HN, Kannan S, Tejasvi C, et al. Study of Effect of Magnesium Sulphate in Management of Acute Organophosphorous Pesticide Poisoning. Anesth Essays Res. 2017;11(1):192-196doi: 10.4103/0259-1162.194585.
Vijayakumar, H. N., Kannan, S., Tejasvi, C., Duggappa, D. R., Veeranna Gowda, K. M., & Nethra, S. S. (2017). Study of Effect of Magnesium Sulphate in Management of Acute Organophosphorous Pesticide Poisoning. Anesthesia, essays and researches, 11(1), 192-196. https://doi.org/10.4103/0259-1162.194585
Vijayakumar, H N, et al. "Study of Effect of Magnesium Sulphate in Management of Acute Organophosphorous Pesticide Poisoning." Anesthesia, essays and researches vol. 11,1 (2017): 192-196. doi: https://doi.org/10.4103/0259-1162.194585
Vijayakumar HN, Kannan S, Tejasvi C, Duggappa DR, Veeranna Gowda KM, Nethra SS. Study of Effect of Magnesium Sulphate in Management of Acute Organophosphorous Pesticide Poisoning. Anesth Essays Res. 2017 Jan-Mar;11(1):192-196. doi: 10.4103/0259-1162.194585. PMID: 28298783; PMCID: PMC5341676.
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Anesth Essays Res. 2017 Jan-Mar;11(1):192-196. doi: 10.4103/0259-1162.194585.

Study of Effect of Magnesium Sulphate in Management of Acute Organophosphorous Pesticide Poisoning.

Anesthesia, essays and researches

H N Vijayakumar, Sudheesh Kannan, C Tejasvi, Devika Rani Duggappa, K M Veeranna Gowda, S S Nethra

Affiliations

  1. Department of Anaesthesia, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
  2. Department of Medicine, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.

PMID: 28298783 PMCID: PMC5341676 DOI: 10.4103/0259-1162.194585

Abstract

BACKGROUND: Organophosphorus compound poisoning (OPCP) is a major public health problem in developing countries like India. Atropine and oximes remain the main-stay of management. Magnesium sulfate (MgSO

AIMS: This study was designed to assess the effect of MgSO

SETTINGS AND DESIGN: Double-blind prospective randomized clinical trial in an ICU of tertiary care institution.

METHODS: One hundred patients (50 in each group) of OPCP, confirmed by history and syndrome of OPCP with low plasma pseudocholinesterase, aged between 18 and 60 years were studied. Magnesium group (Group M) received 4 g of 20% MgSO

STATISTICAL ANALYSIS: Chi-square test and Fisher's exact test for categorical data, independent sample

RESULTS: Demographics and basal serum magnesium levels were comparable. Atropine requirement was higher in Group C (74.82 ± 22.39 mg) compared to Group M (53.11 ± 45.83 mg) (

CONCLUSION: Four grams of MgSO

Keywords: Atropine; Intensive Care Unit; magnesium sulfate; mechanical ventilation; organophosphorus compound poisoning

Conflict of interest statement

There are no conflicts of interest.

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