Display options
Share it on

Anesth Essays Res. 2017 Jan-Mar;11(1):228-232. doi: 10.4103/0259-1162.194579.

Effect of Periradial Administration of Papaverine on Radial Artery Diameter.

Anesthesia, essays and researches

P S Nagaraja, Naveen G Singh, N Manjunatha, Rushikesh Chintamanrao Desai

Affiliations

  1. Department of Cardiac Anaesthesia, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, India.

PMID: 28298790 PMCID: PMC5341672 DOI: 10.4103/0259-1162.194579

Abstract

BACKGROUND: Radial artery cannulation is a skillful procedure. An experienced anesthesiologist might also face difficulty in cannulating a feeble radial pulse.

AIM: The purpose of the study was to determine whether periradial subcutaneous administration of papaverine results in effective vasodilation and improvement in the palpability score of radial artery.

SETTINGS AND DESIGN: Prospective, double-blinded trial.

METHODOLOGY: Thirty patients undergoing elective cardiac surgery were enrolled in the study. 30 mg of papaverine with 1 ml of 2% lignocaine and 3 ml of normal saline were injected subcutaneously 1-2 cm proximal to styloid process of the radius. Radial artery diameter before and after 20 min of injection papaverine was measured using ultrasonography. The palpability of the radial pulse was also determined before the injection of papaverine and 20 min later. Patients were monitored for hemodynamics and any complications were noted.

STATISTICAL ANALYSIS USED: Student's

RESULTS: Radial artery diameter increased significantly (

CONCLUSION: Periradial subcutaneous administration of papaverine significantly increased the radial artery diameter and pulse palpability score, which had an impact on ease of radial artery cannulation essential for hemodynamic monitoring in cardiac surgical patients.

Keywords: Papaverine; pulse palpability score; radial artery

Conflict of interest statement

There are no conflicts of interest.

References

  1. Crit Care. 2002 Jun;6(3):199-204 - PubMed
  2. Catheter Cardiovasc Interv. 2008 Sep 1;72(3):343-6 - PubMed
  3. J Vasc Interv Radiol. 2009 Sep;20(9):1151-6 - PubMed
  4. Eur Heart J. 2001 Dec;22(23):2209-16 - PubMed
  5. Jpn Heart J. 2004 Sep;45(5):723-31 - PubMed
  6. Ann Thorac Cardiovasc Surg. 2001 Apr;7(2):84-8 - PubMed
  7. PLoS One. 2010 Mar 09;5(3):e9601 - PubMed
  8. J Thorac Cardiovasc Surg. 2000 Jan;119(1):94-100 - PubMed
  9. Ann Thorac Surg. 1997 May;63(5):1346-52 - PubMed
  10. Ann Thorac Surg. 1999 Mar;67(3):878-88 - PubMed
  11. J Am Coll Cardiol. 2001 Dec;38(7):1866-71 - PubMed
  12. J Thorac Cardiovasc Surg. 1995 Sep;110(3):697-703 - PubMed
  13. J Thorac Cardiovasc Surg. 2003 Dec;126(6):1798-805 - PubMed
  14. Catheter Cardiovasc Interv. 2006 Sep;68(3):389-91 - PubMed
  15. J Am Coll Cardiol. 2004 Jul 21;44(2):349-56 - PubMed
  16. Rev Esp Cardiol. 2005 May;58(5):504-11 - PubMed
  17. J Invasive Cardiol. 2008 Oct;20(10):551-2 - PubMed

Publication Types