Display options
Cite
Balmer D, Bapst-Wicht L, Pyakurel A, et al. Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Front Aging Neurosci. 2017;9:43doi: 10.3389/fnagi.2017.00043.
Balmer, D., Bapst-Wicht, L., Pyakurel, A., Emery, M., Nanchen, N., Bochet, C. G., & Roduit, R. (2017). Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Frontiers in aging neuroscience, 943. https://doi.org/10.3389/fnagi.2017.00043
Balmer, Delphine, et al. "Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis." Frontiers in aging neuroscience vol. 9 (2017): 43. doi: https://doi.org/10.3389/fnagi.2017.00043
Balmer D, Bapst-Wicht L, Pyakurel A, Emery M, Nanchen N, Bochet CG, Roduit R. Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Front Aging Neurosci. 2017 Mar 01;9:43. doi: 10.3389/fnagi.2017.00043. eCollection 2017. PMID: 28298893; PMCID: PMC5331064.
Copy Download .nbib Format: NLM
Share it on

Front Aging Neurosci. 2017 Mar 01;9:43. doi: 10.3389/fnagi.2017.00043. eCollection 2017.

Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis.

Frontiers in aging neuroscience

Delphine Balmer, Linda Bapst-Wicht, Aswin Pyakurel, Martine Emery, Natacha Nanchen, Christian G Bochet, Raphael Roduit

Affiliations

  1. Institute for Research in Ophthalmology Sion, Switzerland.
  2. Institute for Research in OphthalmologySion, Switzerland; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des AveuglesLausanne, Switzerland.
  3. Department of Chemistry, University of Fribourg Fribourg, Switzerland.

PMID: 28298893 PMCID: PMC5331064 DOI: 10.3389/fnagi.2017.00043

Abstract

Age-related macular degeneration (ARMD) is the leading cause of vision loss in developed countries. Hallmarks of the disease are well known; indeed, this pathology is characterized by lipofuscin accumulation, is principally composed of lipid-containing residues of lysosomal digestion. The

Keywords: A2E; ARPE19; age-related macular degeneration (ARMD); extracellular signal-regulated kinase (ERK); fibroblast growth factor (FGF); mitogen-activated protein kinase (MAPK); retinal metabolism; retinal pigment epithelium cells (RPE)

References

  1. Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1981-9 - PubMed
  2. J Biol Chem. 2000 Dec 15;275(50):39625-30 - PubMed
  3. Invest Ophthalmol Vis Sci. 1998 Mar;39(3):637-44 - PubMed
  4. EMBO J. 2000 Mar 15;19(6):1301-11 - PubMed
  5. Bioessays. 2006 May;28(5):504-14 - PubMed
  6. J Cell Physiol. 1992 Apr;151(1):81-93 - PubMed
  7. Science. 2002 Dec 6;298(5600):1912-34 - PubMed
  8. Invest Ophthalmol Vis Sci. 2013 Aug 15;54(8):5535-42 - PubMed
  9. Dev Dyn. 1997 Aug;209(4):387-98 - PubMed
  10. J Biol Chem. 2008 May 2;283(18):11947-53 - PubMed
  11. BMC Ophthalmol. 2003 Mar 21;3:5 - PubMed
  12. Exp Eye Res. 2014 Sep;126:5-15 - PubMed
  13. J Biol Chem. 2008 Jul 25;283(30):20745-53 - PubMed
  14. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3842-7 - PubMed
  15. J Cell Biochem. 2000 Jan;76(3):354-9 - PubMed
  16. FEBS J. 2010 Jan;277(1):22-9 - PubMed
  17. Apoptosis. 2008 Mar;13(3):343-53 - PubMed
  18. Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3091-8 - PubMed
  19. Trends Biochem Sci. 1994 Nov;19(11):470-3 - PubMed
  20. J Biol Chem. 2013 Nov 29;288(48):34484-93 - PubMed
  21. J Cell Biol. 1999 Dec 27;147(7):1533-48 - PubMed
  22. Biochem Biophys Res Commun. 2005 Nov 11;337(1):241-7 - PubMed
  23. Endocr Rev. 1997 Feb;18(1):26-45 - PubMed
  24. N Engl J Med. 2000 Feb 17;342(7):483-92 - PubMed
  25. Exp Eye Res. 1996 Feb;62(2):155-69 - PubMed
  26. Mol Vis. 2011;17 :2040-8 - PubMed
  27. Physiol Rev. 1999 Jan;79(1):143-80 - PubMed
  28. Proc Natl Acad Sci U S A. 1993 May 1;90(9):4276-80 - PubMed
  29. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16182-7 - PubMed
  30. J Cell Biol. 1998 Jun 29;141(7):1659-73 - PubMed
  31. Apoptosis. 2009 Jan;14(1):31-41 - PubMed
  32. FEBS Lett. 1997 Jul 21;412(1):21-9 - PubMed
  33. Curr Eye Res. 2001 Sep;23(3):185-91 - PubMed
  34. Biochim Biophys Acta. 2010 Apr;1802(4):396-405 - PubMed
  35. J Neurosci. 1992 Sep;12(9):3554-67 - PubMed
  36. Ophthalmic Res. 2011;46(2):88-91 - PubMed
  37. J Biol Chem. 2008 Sep 5;283(36):24770-80 - PubMed
  38. J Stem Cells. 2015;10(3):159-70 - PubMed
  39. J Biol Chem. 2012 Jun 22;287(26):22276-86 - PubMed
  40. N Engl J Med. 2006 Oct 5;355(14):1474-85 - PubMed
  41. Nature. 1990 Sep 6;347(6288):83-6 - PubMed
  42. Mol Vis. 2006 Dec 22;12:1649-59 - PubMed
  43. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17551-6 - PubMed
  44. Invest Ophthalmol Vis Sci. 1999 Nov;40(12):2988-95 - PubMed
  45. J Biol Chem. 2015 Nov 6;290(45):27015-20 - PubMed
  46. Endocr Rev. 2001 Apr;22(2):153-83 - PubMed
  47. Photochem Photobiol. 2010 Jul-Aug;86(4):772-80 - PubMed
  48. Mol Reprod Dev. 1995 Dec;42(4):459-67 - PubMed
  49. Pharmacol Rep. 2006 May-Jun;58(3):353-63 - PubMed
  50. Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2786-94 - PubMed
  51. Exp Eye Res. 1992 Nov;55(5):727-34 - PubMed
  52. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14609-13 - PubMed
  53. J Exp Med. 2004 Dec 20;200(12 ):1539-45 - PubMed
  54. Endocr Relat Cancer. 2000 Sep;7(3):165-97 - PubMed
  55. Genome Biol. 2001;2(3):REVIEWS3005 - PubMed
  56. J Cell Biochem. 1999 Jul 1;74(1):135-43 - PubMed
  57. Nutr Rev. 2003 Oct;61(10):342-6 - PubMed

Publication Types