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Stem Cells Int. 2017;2017:5274171. doi: 10.1155/2017/5274171. Epub 2017 Feb 12.

[No title available]

Stem cells international

Agnese Po, Federica Begalli, Luana Abballe, Vincenzo Alfano, Zein Mersini Besharat, Giuseppina Catanzaro, Alessandra Vacca, Maddalena Napolitano, Marco Tafani, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti, Evelina Miele

Affiliations

  1. Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
  2. Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  3. Department of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy.
  4. Department of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  5. Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy.
  6. Department of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.

PMID: 28298929 PMCID: PMC5337365 DOI: 10.1155/2017/5274171

Abstract

Cell development is regulated by a complex network of mRNA-encoded proteins and microRNAs, all funnelling onto the modulation of self-renewal or differentiation genes. How intragenic microRNAs and their host genes are transcriptionally coregulated and their functional relationships for the control of neural stem cells (NSCs) are poorly understood. We propose here the intragenic miR-326 and its host gene

Conflict of interest statement

The authors declare that there is no conflict of interests regarding the publication of this paper.

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