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Hutter S, Bolin S, Weishaupt H, et al. Modeling and Targeting MYC Genes in Childhood Brain Tumors. Genes (Basel). 2017;8(4)doi: 10.3390/genes8040107.
Hutter, S., Bolin, S., Weishaupt, H., & Swartling, F. J. (2017). Modeling and Targeting MYC Genes in Childhood Brain Tumors. Genes, 8(4), . https://doi.org/10.3390/genes8040107
Hutter, Sonja, et al. "Modeling and Targeting MYC Genes in Childhood Brain Tumors." Genes vol. 8,4 (2017). doi: https://doi.org/10.3390/genes8040107
Hutter S, Bolin S, Weishaupt H, Swartling FJ. Modeling and Targeting MYC Genes in Childhood Brain Tumors. Genes (Basel). 2017 Mar 23;8(4). doi: 10.3390/genes8040107. PMID: 28333115; PMCID: PMC5406854.
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Genes (Basel). 2017 Mar 23;8(4). doi: 10.3390/genes8040107.

Modeling and Targeting MYC Genes in Childhood Brain Tumors.

Genes

Sonja Hutter, Sara Bolin, Holger Weishaupt, Fredrik J Swartling

Affiliations

  1. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden. [email protected].
  2. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden. [email protected].
  3. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden. [email protected].
  4. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden. [email protected].

PMID: 28333115 PMCID: PMC5406854 DOI: 10.3390/genes8040107

Abstract

Brain tumors are the second most common group of childhood cancers, accounting for about 20%-25% of all pediatric tumors. Deregulated expression of the MYC family of transcription factors, particularly

Keywords: MYC; oncogene; pediatric brain tumors; targeted therapy; medulloblastoma; glioma

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