Display options
Share it on

Asian-Australas J Anim Sci. 2017 Oct;30(10):1478-1485. doi: 10.5713/ajas.17.0053. Epub 2017 Mar 21.

[No title available]

Asian-Australasian journal of animal sciences

Hyun Soon Lillehoj, Seung Ik Jang, Alfredo Panebra, Erik Peter Lillehoj, Laurent Dupuis, Juliette Ben Arous, Seung Kyoo Lee, Sung Taek Oh

Affiliations

  1. Animal Biosciences and Biotechnology Laboratory, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA.
  2. Institute of Health and Environment, Daejeon Metropolitan City, Daejeon 305-338, Korea.
  3. Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  4. Seppic, 22 Terrasse Bellini, Puteaux 92800, France.

PMID: 28335090 PMCID: PMC5582334 DOI: 10.5713/ajas.17.0053

Abstract

OBJECTIVE: The effects of vaccinating 18-day-old chicken embryos with the combination of recombinant

METHODS: Eighteen-day-old broiler embryos were injected with 100 μL of phosphate-buffered saline, profilin, profilin plus necrotic enteritis B-like (NetB), profilin plus NetB/Montanide adjuvant (IMS 106), and profilin plus Net-B/Montanide adjuvant (IMS 101). After post-hatch birds were challenged with our NE experimental disease model, body weights, intestinal lesions, serum antibody levels to NetB, and proinflammatory cytokine and chemokine mRNA levels in intestinal intraepithelial lymphocytes were measured.

RESULTS: Chickens

CONCLUSION: These results suggest that the Montanide IMS adjuvants potentiate host immunity to experimentally-induced avian NE when administered

Keywords: Clostridium perfringens; Eimeria; Immunity; In ovo Vaccination; Necrotic Enteritis; Profilin

References

  1. Avian Pathol. 2011 Aug;40(4):341-7 - PubMed
  2. Can Vet J. 1978 Jul;19(7):181-3 - PubMed
  3. Vet Parasitol. 2011 Dec 15;182(2-4):163-70 - PubMed
  4. Adv Drug Deliv Rev. 1999 Jul 26;38(2):167-194 - PubMed
  5. Poult Sci. 2011 Jul;90(7):1381-90 - PubMed
  6. Infect Immun. 2006 Nov;74(11):6496-500 - PubMed
  7. Clin Vaccine Immunol. 2007 Sep;14(9):1070-7 - PubMed
  8. Avian Pathol. 2004 Feb;33(1):83-92 - PubMed
  9. Avian Pathol. 2010 Dec;39(6):489-97 - PubMed
  10. Avian Dis. 2011 Jun;55(2):319-23 - PubMed
  11. Infect Immun. 2004 Dec;72(12):6939-44 - PubMed
  12. Avian Dis. 2008 Mar;52(1):14-22 - PubMed
  13. PLoS Pathog. 2008 Feb 8;4(2):e26 - PubMed
  14. Res Vet Sci. 2011 Dec;91(3):e80-6 - PubMed
  15. Vet Parasitol. 2005 Sep 5;132(1-2):75-80 - PubMed
  16. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):996-1001 - PubMed
  17. Clin Microbiol Rev. 1996 Apr;9(2):216-34 - PubMed
  18. Avian Pathol. 2005 Jun;34(3):159-80 - PubMed
  19. Avian Pathol. 2016 Jun;45(3):295-301 - PubMed
  20. Avian Dis. 2000 Apr-Jun;44(2):379-89 - PubMed
  21. Avian Pathol. 2016 Jun;45(3):313-6 - PubMed
  22. Vaccine. 2010 Nov 16;28(49):7774-8 - PubMed
  23. Biotechniques. 2002 Jun;32(6):1372-4, 1376, 1378-9 - PubMed
  24. Toxins (Basel). 2010 Jul;2(7):1913-27 - PubMed
  25. Vet Immunol Immunopathol. 2008 Mar 15;122(1-2):104-15 - PubMed
  26. Vaccine. 2012 Aug 3;30(36):5401-6 - PubMed
  27. Adv Vet Med. 1999;41:495-515 - PubMed
  28. Avian Dis. 1983 Apr-Jun;27(2):453-63 - PubMed

Publication Types