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Geng Z, Yuan Q, Zhuo X, et al. Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions. Nanomaterials (Basel). 2017;7(2)doi: 10.3390/nano7020038.
Geng, Z., Yuan, Q., Zhuo, X., Li, Z., Cui, Z., Zhu, S., Liang, Y., Liu, Y., Bao, H., Li, X., Huo, Q., & Yang, X. (2017). Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions. Nanomaterials (Basel, Switzerland), 7(2), . https://doi.org/10.3390/nano7020038
Geng, Zhen, et al. "Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions." Nanomaterials (Basel, Switzerland) vol. 7,2 (2017). doi: https://doi.org/10.3390/nano7020038
Geng Z, Yuan Q, Zhuo X, Li Z, Cui Z, Zhu S, Liang Y, Liu Y, Bao H, Li X, Huo Q, Yang X. Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions. Nanomaterials (Basel). 2017 Feb 15;7(2). doi: 10.3390/nano7020038. PMID: 28336873; PMCID: PMC5333023.
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Nanomaterials (Basel). 2017 Feb 15;7(2). doi: 10.3390/nano7020038.

Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions.

Nanomaterials (Basel, Switzerland)

Zhen Geng, Qin Yuan, Xianglong Zhuo, Zhaoyang Li, Zhenduo Cui, Shengli Zhu, Yanqin Liang, Yunde Liu, Huijing Bao, Xue Li, Qianyu Huo, Xianjin Yang

Affiliations

  1. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  2. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. [email protected].
  3. Department of Spinal Surgery, Liuzhou Worker's Hospital, Liuzhou 545001, China. [email protected].
  4. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  5. School of Materials Science and Engineering, Tianjin University, 92 Weijin Road, Tianjin 300072, China. [email protected].
  6. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  7. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  8. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  9. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. [email protected].
  10. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. [email protected].
  11. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. [email protected].
  12. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. [email protected].
  13. Tianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. [email protected].
  14. School of Materials Science and Engineering, Tianjin University, 92 Weijin Road, Tianjin 300072, China. [email protected].

PMID: 28336873 PMCID: PMC5333023 DOI: 10.3390/nano7020038

Abstract

Nanosized hydroxyapatite (HA) is a promising candidate for a substitute for apatite in bone in biomedical applications. Furthermore, due to its excellent bone bioactivity, nanosized strontium-substituted HA (SrHA) has aroused intensive interest. However, the size effects of these nanoparticles on cellular bioactivity should be considered. In this study, nanosized HA and SrHA with different dimensions and crystallization were synthesized by hydrothermal methods. The phase, crystallization and chemical composition were analyzed by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR), respectively. The morphology was observed under field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM). The degradation behaviors of the samples were monitored by determining the ions release profile with inductively coupled plasma mass spectrometry (ICP-MS). The releasing behavior of Ca

Keywords: absorbable implants; biocompatible materials; crystallization; nanostructured materials; surface properties

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