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Wintrob ZA, Hammel JP, Nimako GK, et al. TH1 and TH2 cytokines dataset in insulin users with diabetes mellitus and newly diagnosed breast cancer. Data Brief. 2017;11:331-348doi: 10.1016/j.dib.2017.02.028.
Wintrob, Z. A., Hammel, J. P., Nimako, G. K., Gaile, D. P., Forrest, A., & Ceacareanu, A. C. (2017). TH1 and TH2 cytokines dataset in insulin users with diabetes mellitus and newly diagnosed breast cancer. Data in brief, 11331-348. https://doi.org/10.1016/j.dib.2017.02.028
Wintrob, Zachary A P, et al. "TH1 and TH2 cytokines dataset in insulin users with diabetes mellitus and newly diagnosed breast cancer." Data in brief vol. 11 (2017): 331-348. doi: https://doi.org/10.1016/j.dib.2017.02.028
Wintrob ZA, Hammel JP, Nimako GK, Gaile DP, Forrest A, Ceacareanu AC. TH1 and TH2 cytokines dataset in insulin users with diabetes mellitus and newly diagnosed breast cancer. Data Brief. 2017 Feb 20;11:331-348. doi: 10.1016/j.dib.2017.02.028. eCollection 2017 Apr. PMID: 28275667; PMCID: PMC5328909.
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Data Brief. 2017 Feb 20;11:331-348. doi: 10.1016/j.dib.2017.02.028. eCollection 2017 Apr.

TH1 and TH2 cytokines dataset in insulin users with diabetes mellitus and newly diagnosed breast cancer.

Data in brief

Zachary A P Wintrob, Jeffrey P Hammel, George K Nimako, Dan P Gaile, Alan Forrest, Alice C Ceacareanu

Affiliations

  1. State University of New York at Buffalo, Department of Pharmacy Practice, NYS Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, NY 14203, USA.
  2. Cleveland Clinic, Dept. of Biostatistics and Epidemiology, 9500 Euclid Ave., Cleveland, OH 44195, USA.
  3. State University of New York at Buffalo, Department of Biostatistics, 718 Kimball Tower, Buffalo, NY 14214, USA.
  4. The UNC Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, Campus Box 7569, Chapel Hill, NC 27599, USA.
  5. State University of New York at Buffalo, Department of Pharmacy Practice, NYS Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, NY 14203, USA; Roswell Park Cancer Institute, Dept. of Pharmacy Services, Elm & Carlton Streets, Buffalo, NY 14263, USA.

PMID: 28275667 PMCID: PMC5328909 DOI: 10.1016/j.dib.2017.02.028

Abstract

Exogenous insulin use may interfere with the T helper cells' cytokine production. This dataset presents the relationship between pre-existing use of injectable insulin in women diagnosed with breast cancer and type 2 diabetes mellitus, the T-helper 1 and 2 produced cytokine profiles at the time of breast cancer diagnosis, and subsequent cancer outcomes. A Pearson correlation analysis evaluating the relationship between T-helper cytokines stratified by of insulin use and controls is also provided.

Keywords: Breast cancer; Cancer outcomes; Cancer prognosis; Cytokine; Diabetes; Insulin; TH1 cytokine; TH2 cytokine; Type 1 T helper cytokine; Type 2 T helper cytokine

References

  1. Cytokine. 2017 Jan;89:45-61 - PubMed

Publication Types

Grant support