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Drazin D, Kappel A, Withrow S, et al. Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature. Surg Neurol Int. 2017;8:26doi: 10.4103/2152-7806.200574.
Drazin, D., Kappel, A., Withrow, S., Perry, T., Chu, R., & Phuphanich, S. (2017). Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature. Surgical neurology international, 826. https://doi.org/10.4103/2152-7806.200574
Drazin, Doniel, et al. "Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature." Surgical neurology international vol. 8 (2017): 26. doi: https://doi.org/10.4103/2152-7806.200574
Drazin D, Kappel A, Withrow S, Perry T, Chu R, Phuphanich S. Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature. Surg Neurol Int. 2017 Feb 20;8:26. doi: 10.4103/2152-7806.200574. eCollection 2017. PMID: 28303206; PMCID: PMC5339903.
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Surg Neurol Int. 2017 Feb 20;8:26. doi: 10.4103/2152-7806.200574. eCollection 2017.

Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature.

Surgical neurology international

Doniel Drazin, Ari Kappel, Stefan Withrow, Tiffany Perry, Ray Chu, Surasak Phuphanich

Affiliations

  1. Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
  2. School of Medicine, Stony Brook University, New York, USA.
  3. Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California.

PMID: 28303206 PMCID: PMC5339903 DOI: 10.4103/2152-7806.200574

Abstract

BACKGROUND: Multiple radiation-induced cavernous malformations of the cauda equina are extremely rare. A review of the literature suggested that the post-irradiation lumbosacral radiculopathy in our patient was most likely associated with a diagnosis of multiple radiation-induced cavernous malformations of the cauda equina.

CASE DESCRIPTION: A 76-year-old man with a remote history of abdominal radiation therapy presented with a 6-month history of progressively worsening right foot drop and balance impairment. Magnetic resonance imaging (MRI) revealed multiple enhancing areas of the cauda equina concerning for carcinomatous meningitis, however, cerebrospinal fluid (CSF) analysis was unrevealing. Intraoperative findings were consistent with multiple radiation-induced cavernous malformations of the cauda equina.

CONCLUSIONS: Multiple radiation-induced cavernous malformations of the cauda equina may mimic carcinomatous or infectious meningitis. Clinicians should be suspicious of this diagnosis when CSF and MRI findings are inconsistent with metastatic disease or infectious meningitis in patients who present with radiculopathy and a history of radiation therapy.

Keywords: Cauda equina; cavernous malformation; radiculopathy; radiotherapy; spine

Conflict of interest statement

There are no conflicts of interest.

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