Pak J Med Sci. 2017 Jan-Feb;33(1):137-141. doi: 10.12669/pjms.331.11168.
The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome.
Pakistan journal of medical sciences
Funda Erbasan, Yesim Cekin, Deniz Turgut Coban, Ugur Karasu, Dinc Suren, Ayhan H Cekin
Affiliations
Affiliations
- Funda Erbasan, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
- Yesim Cekin, MD. Associate Professor, Department of Microbiology, Antalya Training and Research Hospital, Antalya, Turkey.
- Deniz Turgut Coban, MD. Specialist, Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey.
- Ugur Karasu, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
- Dinc Suren, MD. Associate Professor, Department of Pathology, Antalya Training and Research Hospital, Antalya, Turkey.
- Ayhan H. Cekin, MD. Associate Professor, Department of Gastroenterology, Antalya Training and Research Hospital, Antalya, Turkey.
PMID: 28367187
PMCID: PMC5368295 DOI: 10.12669/pjms.331.11168
Abstract
OBJECTIVE: To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).
METHODS: Seventy seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed. And the diagnosis of SS was made according to the American College of Rheumatology (ACR) classification criteria for SS - 2012.
RESULTS: Thirteen (16.9%) of IBS patients had FM. Dry eye was detected in 20(26.0%), 7(9.1%) and 29(37.7%) patients by OSS, Schirmer test and TBUT, respectively. Of 77 patients with IBS, the diagnosis of SS was established in two patients (2.6%).
CONCLUSION: The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.
Keywords: Antinuclear antibodies; Fibromyalgia; Irritable Bowel Syndrome; Sjogren’s Syndrome
Conflict of interest statement
Declaration of interest: None.
References
- Am J Gastroenterol. 1999 Jul;94(7):1898-901 - PubMed
- Postgrad Med. 1998 Feb;103(2):93-100 - PubMed
- Int J Environ Res Public Health. 2015 Jul 08;12(7):7647-55 - PubMed
- Acta Ophthalmol Scand. 1997 Jun;75(3):281-6 - PubMed
- Arthritis Care Res (Hoboken). 2012 Apr;64(4):475-87 - PubMed
- J Rheumatol. 2010 Nov;37(11):2313-8 - PubMed
- Scand J Rheumatol. 2007 Sep-Oct;36(5):394-401 - PubMed
- Arch Intern Med. 2000 Jan 24;160(2):221-7 - PubMed
- Gastroenterology. 2006 Apr;130(5):1377-90 - PubMed
- Clin Rheumatol. 2002 Nov;21(6):472-7 - PubMed
- Gastroenterology. 2015 Sep;149(3):596-603.e1 - PubMed
- Rheumatol Int. 2007 Sep;27(11):1031-9 - PubMed
- Clin Gastroenterol Hepatol. 2012 Jul;10(7):712-721.e4 - PubMed
- Rheumatology (Oxford). 2006 Feb;45(2):187-91 - PubMed
- Gastroenterology. 2002 Apr;122(4):1140-56 - PubMed
- J Rheumatol. 1986 Apr;13(2):368-73 - PubMed
- J Rheumatol. 1992 Jan;19(1):110-4 - PubMed
- Gynecol Obstet Invest. 1994;37(3):160-3 - PubMed
- Arthritis Care Res (Hoboken). 2010 May;62(5):600-10 - PubMed
- J Autoimmun. 2012 Aug;39(1-2):15-26 - PubMed
- Nihon Rinsho. 1995 Oct;53(10):2367-70 - PubMed
- J Clin Pathol. 1968 Sep;21(5):656-60 - PubMed
- Semin Arthritis Rheum. 2000 Feb;29(4):197-9 - PubMed
- Gut. 1986 Jan;27(1):37-40 - PubMed
- Ophthalmic Epidemiol. 2009 Jan-Feb;16(1):15-21 - PubMed
- Dig Dis Sci. 2006 Mar;51(3):454-60 - PubMed
- Int J Dermatol. 2002 Jul;41(7):417-22 - PubMed
- Scand J Rheumatol. 2009;38(5):391-3 - PubMed
- Ophthalmic Epidemiol. 2010 Aug;17(4):234-41 - PubMed
Publication Types