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Meulemans J, Delaere P, Nuyts S, et al. Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes. Curr Otorhinolaryngol Rep. 2017;5(1):83-91doi: 10.1007/s40136-017-0143-7.
Meulemans, J., Delaere, P., Nuyts, S., Clement, P. M., Hermans, R., & Vander Poorten, V. (2017). Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes. Current otorhinolaryngology reports, 5(1), 83-91. https://doi.org/10.1007/s40136-017-0143-7
Meulemans, J, et al. "Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes." Current otorhinolaryngology reports vol. 5,1 (2017): 83-91. doi: https://doi.org/10.1007/s40136-017-0143-7
Meulemans J, Delaere P, Nuyts S, Clement PM, Hermans R, Vander Poorten V. Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes. Curr Otorhinolaryngol Rep. 2017;5(1):83-91. doi: 10.1007/s40136-017-0143-7. Epub 2017 Feb 07. PMID: 28367362; PMCID: PMC5357496.
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Curr Otorhinolaryngol Rep. 2017;5(1):83-91. doi: 10.1007/s40136-017-0143-7. Epub 2017 Feb 07.

Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes.

Current otorhinolaryngology reports

J Meulemans, P Delaere, S Nuyts, P M Clement, R Hermans, V Vander Poorten

Affiliations

  1. Department of Otorhinolaryngology-Head and Neck Surgery, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
  2. Department of Oncology, Section Head and Neck Oncology, KU Leuven, Leuven, Belgium.
  3. Department of Radiotherapy, University Hospitals Leuven, Leuven, Belgium.
  4. Department of Oncology, Section Experimental Radiotherapy, KU Leuven, Leuven, Belgium.
  5. Department of Medical Oncology, University Hospitals Leuven, Leuven, Belgium.
  6. Department of Radiology, University Hospitals Leuven, Leuven, Belgium.

PMID: 28367362 PMCID: PMC5357496 DOI: 10.1007/s40136-017-0143-7

Abstract

PURPOSE OF REVIEW: The aim of this report is to identify relevant literature reports on salvage transoral laser microsurgery (TLM); to consider its oncologic and functional outcomes, as well as reported complications; and to address indications and limitations of salvage TLM.

FINDINGS: The weighted average of local control after first salvage TLM was 57%. Repeated TLM procedures for second or third recurrences were required in up to 41% of cases, resulting in a weighted average of local control with TLM alone of 67%. The rate of definite laryngeal preservation was 73%. The ultimate local control rate, including cases that required total laryngectomy, was 90%. The overall complication rate after salvage TLM was 14%.

SUMMARY: Salvage TLM of radiorecurrent laryngeal cancer yields excellent oncologic outcomes. Serious complications are scarce, hospitalization times are short, and functional outcomes in terms of voice and swallowing are favorable when compared to open conservation laryngeal surgery. The key to success is an optimal patient selection.

Keywords: Conservation surgery; Laryngeal cancer; Salvage surgery; Squamous cell carcinoma; Transoral laser microsurgery

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