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Dubey S, Saha SG, Rajkumar B, et al. Comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection. Eur J Dent. 2017;11(1):12-16doi: 10.4103/ejd.ejd_141_16.
Dubey, S., Saha, S. G., Rajkumar, B., & Dhole, T. K. (2017). Comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection. European journal of dentistry, 11(1), 12-16. https://doi.org/10.4103/ejd.ejd_141_16
Dubey, Sandeep, et al. "Comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection." European journal of dentistry vol. 11,1 (2017): 12-16. doi: https://doi.org/10.4103/ejd.ejd_141_16
Dubey S, Saha SG, Rajkumar B, Dhole TK. Comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection. Eur J Dent. 2017 Jan-Mar;11(1):12-16. doi: 10.4103/ejd.ejd_141_16. PMID: 28435359; PMCID: PMC5379824.
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Eur J Dent. 2017 Jan-Mar;11(1):12-16. doi: 10.4103/ejd.ejd_141_16.

Comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection.

European journal of dentistry

Sandeep Dubey, Suparna Ganguly Saha, Balakrishnan Rajkumar, Tapan Kumar Dhole

Affiliations

  1. Department of Conservative Dentistry and Endodontics, College of Dental Sciences and Hospital, Indore, Madhya Pradesh, India.
  2. Department of Conservative Dentistry and Endodontics, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
  3. Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

PMID: 28435359 PMCID: PMC5379824 DOI: 10.4103/ejd.ejd_141_16

Abstract

OBJECTIVE: This study aims to evaluate and compare the antimicrobial efficacy of three selected root canal irrigants (BioPure MTAD, metronidazole, aztreonam) against microbes commonly isolated from polymicrobial microbiota of root canal infection.

MATERIALS AND METHODS: This study was designed with four experimental groups (Group I -

RESULTS: Metronidazole was found to be the most effective root canal irrigant against

CONCLUSIONS: Overall, BioPure MTAD is the most effective root canal irrigant as it has shown an antibacterial effect against all the tested microorganisms. However, metronidazole showed maximum antibacterial effect against obligate anaerobes. Aztreonam also showed an antibacterial effect in the present study, raising its possibility to be used as a root canal irrigant in the future.

Keywords: Agar disc diffusion method; BioPure MTAD; Candida albicans; Enterococcus faecalis

Conflict of interest statement

There are no conflicts of interest.

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