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Bolge SC, Eldridge HM, Lofland JH, et al. Patient experience with intravenous biologic therapies for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis. Patient Prefer Adherence. 2017;11:661-669doi: 10.2147/PPA.S121032.
Bolge, S. C., Eldridge, H. M., Lofland, J. H., Ravin, C., Hart, P. J., & Ingham, M. P. (2017). Patient experience with intravenous biologic therapies for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis. Patient preference and adherence, 11661-669. https://doi.org/10.2147/PPA.S121032
Bolge, Susan C, et al. "Patient experience with intravenous biologic therapies for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis." Patient preference and adherence vol. 11 (2017): 661-669. doi: https://doi.org/10.2147/PPA.S121032
Bolge SC, Eldridge HM, Lofland JH, Ravin C, Hart PJ, Ingham MP. Patient experience with intravenous biologic therapies for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis. Patient Prefer Adherence. 2017 Mar 28;11:661-669. doi: 10.2147/PPA.S121032. eCollection 2017. PMID: 28405158; PMCID: PMC5378465.
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Patient Prefer Adherence. 2017 Mar 28;11:661-669. doi: 10.2147/PPA.S121032. eCollection 2017.

Patient experience with intravenous biologic therapies for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis.

Patient preference and adherence

Susan C Bolge, Helen M Eldridge, Jennifer H Lofland, Caitlin Ravin, Philip J Hart, Michael P Ingham

Affiliations

  1. Health Economics and Outcomes Research, Janssen Scientific Affairs, LLC, Raritan.
  2. Payer Provider Insights & Analytics, Janssen Services, LLC, Titusville, NJ.
  3. Health Economics and Outcomes Research, Janssen Scientific Affairs, LLC, Horsham, PA.
  4. Value Communications, Medaxial Group, New York, NY, USA.

PMID: 28405158 PMCID: PMC5378465 DOI: 10.2147/PPA.S121032

Abstract

OBJECTIVE: The objective of this study was to describe patient experience with intravenous (IV) biologics for ankylosing spondylitis, Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, or ulcerative colitis.

METHODS: Semi-structured telephone interviews were conducted in 405 patients with these autoimmune diseases who were receiving an IV biologic to treat their disease.

RESULTS: On a 7-point scale (1= not at all satisfied; 7= very satisfied), mean satisfaction with IV medication was rated 6.1; 77% of patients rated satisfaction as 6 or 7. The most frequently perceived benefits of IV therapy were related to supervision provided by health care professionals. Most patients (82%, n=332) preferred their IV medication to subcutaneous injection. The three most common reasons for preferring IV were not wanting to self-inject (43%), less frequent dosing (34%), and preference for administration by a health care professional (24%). African-American/black patients had a stronger preference for IV administration than Caucasian/white patients (97% vs 80%,

CONCLUSION: Users of IV biologics are highly satisfied with their medications and perceive the opportunity for health care provider interaction at their infusion facilities as an advantage of their regimen. These findings support continued need for IV therapeutic options and shared decision-making between patients and physicians while selecting biologic treatments.

Keywords: anti-TNF; biologic; intravenous; patient experience; preference; subcutaneous

Conflict of interest statement

Disclosure At the time of the research SC Bolge, JH Lofland, C Ravin, and MP Ingham were employees of Janssen Scientific Affairs, LLC and H Eldridge was an employee of Janssen Services, LLC. SC Bolge,

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