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Greco F, Faiella E, Santucci D, et al. Imaging of Renal Medullary Carcinoma. J Kidney Cancer VHL. 2017;4(1):1-7doi: 10.15586/jkcvhl.2017.62.
Greco, F., Faiella, E., Santucci, D., Mallio, C. A., Nezzo, M., Quattrocchi, C. C., Beomonte Zobel, B., & Grasso, R. F. (2017). Imaging of Renal Medullary Carcinoma. Journal of kidney cancer and VHL, 4(1), 1-7. https://doi.org/10.15586/jkcvhl.2017.62
Greco, Federico, et al. "Imaging of Renal Medullary Carcinoma." Journal of kidney cancer and VHL vol. 4,1 (2017): 1-7. doi: https://doi.org/10.15586/jkcvhl.2017.62
Greco F, Faiella E, Santucci D, Mallio CA, Nezzo M, Quattrocchi CC, Beomonte Zobel B, Grasso RF. Imaging of Renal Medullary Carcinoma. J Kidney Cancer VHL. 2017 Mar 21;4(1):1-7. doi: 10.15586/jkcvhl.2017.62. eCollection 2017. PMID: 28405543; PMCID: PMC5364331.
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J Kidney Cancer VHL. 2017 Mar 21;4(1):1-7. doi: 10.15586/jkcvhl.2017.62. eCollection 2017.

Imaging of Renal Medullary Carcinoma.

Journal of kidney cancer and VHL

Federico Greco, Eliodoro Faiella, Domiziana Santucci, Carlo Augusto Mallio, Marco Nezzo, Carlo Cosimo Quattrocchi, Bruno Beomonte Zobel, Rosario Francesco Grasso

Affiliations

  1. Unit of Diagnostic Imaging, Università Campus Bio-Medico di Roma, Rome, Italy.

PMID: 28405543 PMCID: PMC5364331 DOI: 10.15586/jkcvhl.2017.62

Abstract

Renal medullary carcinoma (RMC) is a rare, highly aggressive tumor recognized as an independent pathological entity. African-descent adolescents and young adults with sickle cell hemoglobinopathy are the most affected groups. This rare subtype of renal cell carcinoma has its own morphogenetic and pathological characteristics. The major clinical manifestations include gross hematuria, abdominal or flank pain, and weight loss. The prognosis is very poor, with 95% of cases diagnosed at an advanced stage of the disease. In this review, we summarize the morphologic and dynamic characteristics of RMC under various imaging modalities such as ultrasound, computed tomography, and magnetic resonance. Differential diagnosis and management strategies are also discussed.

Keywords: Computed tomography; contrast-enhanced ultrasound; magnetic resonance imaging; renal cell carcinoma; renal medullary carcinoma

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