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Pokorney SD, Rao M, Nilsson KR, et al. Atrial Fibrillation Complicating Acute Coronary Syndromes. J Atr Fibrillation. 2012;5(3):611doi: 10.4022/jafib.611.
Pokorney, S. D., Rao, M., Nilsson, K. R., & Piccini, J. P. (2012). Atrial Fibrillation Complicating Acute Coronary Syndromes. Journal of atrial fibrillation, 5(3), 611. https://doi.org/10.4022/jafib.611
Pokorney, Sean D, et al. "Atrial Fibrillation Complicating Acute Coronary Syndromes." Journal of atrial fibrillation vol. 5,3 (2012): 611. doi: https://doi.org/10.4022/jafib.611
Pokorney SD, Rao M, Nilsson KR, Piccini JP. Atrial Fibrillation Complicating Acute Coronary Syndromes. J Atr Fibrillation. 2012 Oct 06;5(3):611. doi: 10.4022/jafib.611. eCollection 2012. PMID: 28496773; PMCID: PMC5153213.
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J Atr Fibrillation. 2012 Oct 06;5(3):611. doi: 10.4022/jafib.611. eCollection 2012.

Atrial Fibrillation Complicating Acute Coronary Syndromes.

Journal of atrial fibrillation

Sean D Pokorney, Meena Rao, Kent R Nilsson, Jonathan P Piccini

Affiliations

  1. Duke Center for Atrial Fibrillation/Cardiac Electrophysiology Section, Division of Cardiology, Duke University Medical Center.
  2. Claude D. Pepper Center Older American Independence Center.
  3. Duke Clinical Research Institute, Durham, NC.

PMID: 28496773 PMCID: PMC5153213 DOI: 10.4022/jafib.611

Abstract

Atrial fibrillation frequently complicates myocardial infarction. Patients with atrial fibrillation complicating acute coronary syndrome have increased morbidity and mortality relative to patients that remain in normal sinus rhythm. No studies have identified a mortality benefit to rhythm control compared with rate control in the setting of acute coronary syndrome. Stroke prevention should be pursued with oral anticoagulation therapy, although the majority of patients with atrial fibrillation associated with acute coronary syndrome receive only antiplatelet therapy. There are several novel oral anticoagulant therapies now available, but these agents have not been well studied in combination with dual antiplatelet therapy. Therefore, warfarin as part of triple therapy is the most conservative approach until additional data becomes available.

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